Inappropriate Use of Aspirin in Real-Life Cardiology Practice: Results from the Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) Study

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dc.authoridBAŞARAN, ÖZCAN/0000-0002-6384-6455
dc.authoridAltuntaş, Emine/0000-0001-5887-5422
dc.authoridDemirtas, Abdullah Orhan/0000-0003-4768-0536
dc.authoridKaya, Caglar/0000-0002-2968-5352
dc.authoridMemic Sancar, Kadriye/0000-0003-1350-215X
dc.authoridBekar, Lutfu/0000-0002-3920-1382
dc.authoridKiris, Tuncay/0000-0001-9793-718X
dc.authorwosidorscelik, özcan/A-6242-2016
dc.authorwosidTANIK, VEYSEL OZAN/AAC-6308-2020
dc.authorwosidBaşaran, Özcan/KIM-2166-2024
dc.authorwosidÖZLEK, BÜLENT/JLL-5279-2023
dc.authorwosiddemirci, erkan/IVH-2862-2023
dc.authorwosidBAŞARAN, ÖZCAN/H-4217-2019
dc.authorwosidAltuntaş, Emine/HGE-0409-2022
dc.contributor.authorCelik, Oguzhan
dc.contributor.authorCil, Cem
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorDemirci, Erkan
dc.contributor.authorTanik, Veysel Ozan
dc.contributor.authorAltuntas, Emine
dc.contributor.authorSancar, Kadriye Memic
dc.date.accessioned2024-06-12T11:17:47Z
dc.date.available2024-06-12T11:17:47Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Indications and appropriateness of aspirin use have not been well investigated in Turkey. Aims: To investigate the prescription patterns and appropriateness of aspirin in a real-world clinical setting. Study Design: Cross-sectional study. Methods: The Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) is a cross-sectional and multicenter study that included 5007 consecutive patients aged 18 or over who presented to 30 different cardiology outpatient clinics from 14 cities throughout Turkey. Only patients using aspirin (80-325 mg) were included. The study population was divided into 2 groups regarding the use of aspirin: primary prevention (PP) group and secondary prevention (SP) group. The indication of aspirin use was evaluated following the 2016 European Society of Cardiology (ESC) and the 2016 United States Preventative Services Task Force (USPTF) guidelines in the PP group. Results: A total of 5007 patients (mean age 62.15 +/- 11.05, 39% female) were enrolled. The PP group included 1132 (22.6%) patients, and the SP group included 3875 (77.4%) patients. Of the 1132 patients, inappropriate use of aspirin was determined in 100% of the patients according to the ESC guidelines, and 71% of the patients according to the USPTF guidelines. Multivariate logistic regression analysis showed age OR: 0.98 CI (0.97-0.99) P=.037, smoking OR: 0.60 CI (0.44- 0.82) P=.001, heart failure OR: 2.11 CI (1.14-3.92) P=.017, hypertension OR: 0.51 CI (0.36-0.74) P<.001, diabetes mellitus OR: 0.34 CI (0.25-0.47) P<.001, oral anticoagulant use OR: 3.01 CI (1.10-8.25) P=.032, and female sex OR: 2.73 CI (1.96-3.80) P<.001 were independent predictors of inappropriate aspirin use in PP patients. Conclusion: Although there are considerable differences between the USPTF and the ESC guidelines with respect to recommendations for aspirin use in PP, inappropriate use of aspirin in Turkey is frequent in real-world practice for both guidelines. Besides, heart failure, oral anticoagulant use, and the female sex of the patients were independent predictors of inappropriate use of aspirin.en_US
dc.identifier.doi10.5152/balkanmedj.2021.21143
dc.identifier.endpage189en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue3en_US
dc.identifier.pmid34142960en_US
dc.identifier.scopus2-s2.0-85108188968en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage183en_US
dc.identifier.trdizinid465142en_US
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2021.21143
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/465142
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24842
dc.identifier.volume38en_US
dc.identifier.wosWOS:000657512500007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectPrimary Preventionen_US
dc.subjectUnstable Anginaen_US
dc.subjectHeart-Failureen_US
dc.subjectTask-Forceen_US
dc.subjectTherapyen_US
dc.subjectRisken_US
dc.titleInappropriate Use of Aspirin in Real-Life Cardiology Practice: Results from the Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) Studyen_US
dc.typeArticleen_US

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