A Synopsis of Current Practice in the Diagnosis and Management of Patients with Turner Syndrome in Turkey: A Survey of 18 Pediatric Endocrinology Centers

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dc.authoridKİLİNC UGURLU, Aylin/0000-0003-1265-4952
dc.authoridAbaci, Ayhan/0000-0002-1812-0321
dc.authoridDündar, Bumin/0000-0002-7506-061X
dc.authorwosidKİLİNC UGURLU, Aylin/AGB-8554-2022
dc.authorwosidCatli, Gönül/AFT-1499-2022
dc.authorwosidAbaci, Ayhan/A-4356-2016
dc.authorwosidUçar, Ahmet/B-4795-2013
dc.authorwosidDündar, Bumin/JVE-1747-2024
dc.contributor.authorUcar, Ahmet
dc.contributor.authorAbaci, Ayhan
dc.contributor.authorPirgon, Ozgur
dc.contributor.authorDundar, Bumin
dc.contributor.authorTutunculer, Filiz
dc.contributor.authorCatli, Gonul
dc.contributor.authorAnik, Ahmet
dc.date.accessioned2024-06-12T11:16:48Z
dc.date.available2024-06-12T11:16:48Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: A comprehensive survey was conducted to evaluate the shortcomings of clinical care in patients with Turner syndrome (TS) in Turkey. Methods: A structured questionnaire prepared by the Turner study group in Turkey, which covered relevant aspects of patient care in TS was sent to 44 pediatric endocrinology centers. Results: Eighteen centers (41%) responded to the questionnaire. In the majority of the centers, diagnostic genetic testing, screening for Y chromosomal material, protocols regarding the timing and posology of growth hormone (GH) and estrogen, thrombophilia screening, fertility information and screening for glucose intolerance, thyroid, and coeliac diseases in patients with TS were in line with the current consensus. Thirteen centers (72.2%) performed GH stimulation tests. Only four centers (22.2%) used oxandrolone in patients with TS with very short stature. The majority of the centers relied on bone age and breast development to assess estrogen adequacy, though together with variable combinations of oestrogen surrogates. Two centers (11.1%) reported performing serum estradiol measurements. Eight centers (44.4%) routinely conducted cardiac/thoracic aorta magnetic resonance imaging. Screening for hearing, dental and ophthalmologic problems were performed by thirteen (72.2%), six (33.3%) and ten (55.6%) centers, respectively. Psychiatric assessments were made by four centers (22.2%) at diagnosis, with only one center (5.6%) requiring annual reassessments. Conclusion: Although we found some conformity between the current consensus and practice of the participating centers in Turkey regarding TS, further improvements are mandatory in the multi-disciplinary approach to address co-morbidities, which if unrecognized, may be associated with reduced quality of life and even mortality.en_US
dc.identifier.doi10.4274/jcrpe.0003
dc.identifier.endpage238en_US
dc.identifier.issn1308-5727
dc.identifier.issn1308-5735
dc.identifier.issue3en_US
dc.identifier.pmid29699389en_US
dc.identifier.scopus2-s2.0-85051107739en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage230en_US
dc.identifier.trdizinid307871en_US
dc.identifier.urihttps://doi.org/10.4274/jcrpe.0003
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/307871
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24462
dc.identifier.volume10en_US
dc.identifier.wosWOS:000440379800006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of Clinical Research In Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTurner Syndromeen_US
dc.subjectDiagnosisen_US
dc.subjectGrowthen_US
dc.subjectPubertyen_US
dc.subjectOestrogenen_US
dc.subjectOxandroloneen_US
dc.subjectOsteoporosisen_US
dc.subjectAdult Transitionen_US
dc.subjectScreeningen_US
dc.subjectCardiac Magnetic Resonance Imagingen_US
dc.subjectThoracic Aortaen_US
dc.subjectY-Chromosome Materialen_US
dc.subjectAdult Health-Careen_US
dc.subjectWomenen_US
dc.subjectEstrogenen_US
dc.subjectTransitionen_US
dc.subjectBoneen_US
dc.subjectGonadoblastomaen_US
dc.subjectMetaanalysisen_US
dc.subjectGuidelineen_US
dc.subjectPatternsen_US
dc.titleA Synopsis of Current Practice in the Diagnosis and Management of Patients with Turner Syndrome in Turkey: A Survey of 18 Pediatric Endocrinology Centersen_US
dc.typeArticleen_US

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