Manic Shift Due to the Use of Bupropion in Bipolar Depression: Two Case Reports

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dc.authorid, Rugül/0000-0003-2596-0473
dc.authoridGorgulu, Yasemin/0000-0002-3401-4879
dc.authorwosidçınar, rugül köse/S-8927-2019
dc.authorwosid, Rugül/AAI-1711-2019
dc.authorwosidGorgulu, Yasemin/S-4355-2017
dc.contributor.authorKahyaci Kilic, Evnur
dc.contributor.authorGorgulu, Yasemin
dc.contributor.authorKose Cinar, Rugul
dc.contributor.authorBulent Sonmez, Mehmet
dc.date.accessioned2024-06-12T10:55:26Z
dc.date.available2024-06-12T10:55:26Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBupropion is a selective norepinephrine and dopamine reuptake inhibitor. It is used in the treatment of depression and nicotine addiction. When compared to the other antidepressants, bupropion has a relatively lower risk of triggering shift to hypomania or mania in bipolar depression treatment. Here we report two cases of bipolar depression patients with manic shift when bupropion was used as an adjunct to mood stabilizer treatment. The first was a 43-year old female patient. Manic symptoms occurred after bupropion was added to lithium and quetiapine treatment for bipolar disorder (BD) depressive episode. Her manic symptoms regressed rapidly after discontinuing bupropion treatment. The second patient was a 26-year old male on lithium and valproate therapy with a BD diagnosis. After bupropion was added to his treatment for depressive symptoms, psychotic mania ensued and he had to be admitted to the hospital. Significant improvement was noted shortly after bupropion was discontinued and antipsychotic treatment was initiated.en_US
dc.identifier.doi10.5080/u23391
dc.identifier.endpage148en_US
dc.identifier.issn1300-2163
dc.identifier.issue2en_US
dc.identifier.pmid31487381en_US
dc.identifier.scopus2-s2.0-85071763496en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage145en_US
dc.identifier.trdizinid357403en_US
dc.identifier.urihttps://doi.org/10.5080/u23391
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/357403
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19411
dc.identifier.volume30en_US
dc.identifier.wosWOS:000496714500010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTurkiye Sinir Ve Ruh Sagligi Dernegien_US
dc.relation.ispartofTurk Psikiyatri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBupropionen_US
dc.subjectBipolar Disorderen_US
dc.subjectDepressionen_US
dc.subjectManiaen_US
dc.subjectAntidepressant-Induced Maniaen_US
dc.subjectSwitchen_US
dc.subjectHypomaniaen_US
dc.subjectRisken_US
dc.subjectVenlafaxineen_US
dc.subjectDisordersen_US
dc.titleManic Shift Due to the Use of Bupropion in Bipolar Depression: Two Case Reportsen_US
dc.typeArticleen_US

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