Oxcarbazepine-induced Stevens-Johnson syndrome: a pediatric case report

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dc.authoridBeken, Burcin/0000-0001-7677-7690;
dc.authorwosidCan, Nuray/D-3452-2016
dc.authorwosidBeken, Burcin/GPK-8389-2022
dc.authorwosidYazicioglu, Mehtap/AAB-9587-2022
dc.contributor.authorBeken, Burcin
dc.contributor.authorCan, Ceren
dc.contributor.authorOrencik, Aysegul
dc.contributor.authorCan, Nuray
dc.contributor.authorYazicioglu, Mehtap
dc.date.accessioned2024-06-12T11:20:06Z
dc.date.available2024-06-12T11:20:06Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis are two rare but life-threatening diseases characterized by detachment of epidermis, bullous skin lesions and mucous membrane erosions. Anti-epileptic drugs are highly suspected to be the causative agents. Although carbamazepine (CBZ) is the most associated anti-epileptic drug, oxcarbazepine (OXC), which is a monohydrated derivative of CBZ, is proposed to be safer because of the different metabolism of the two drugs. Herein, we report a case of SJS induced by oxcarbazepine. A 6-year-old boy with benign rolandic epilepsy, admitted to our hospital with generalized maculopapular rash after starting oxcarbazepine. The diagnosis of SJS was made with cytotoxic skin lesions and mucous membrane involvement. After discontinuing of the drug and topical corticosteroid initiation, the lesions were improved. We report this case to attract attention to the serious side effect of this anti-epileptic drug.en_US
dc.identifier.doi10.1093/omcr/omx028
dc.identifier.endpage81en_US
dc.identifier.issn2053-8855
dc.identifier.issue6en_US
dc.identifier.pmid28580160en_US
dc.identifier.scopus2-s2.0-85021297622en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage79en_US
dc.identifier.urihttps://doi.org/10.1093/omcr/omx028
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25467
dc.identifier.wosWOS:000418513300003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofOxford Medical Case Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectToxic Epidermal Necrolysisen_US
dc.subjectT-Cellsen_US
dc.subjectCarbamazepineen_US
dc.titleOxcarbazepine-induced Stevens-Johnson syndrome: a pediatric case reporten_US
dc.typeArticleen_US

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