Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis

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dc.authoridGüçlü, Hande/0000-0002-3021-0493
dc.authoridBirgul, Ramazan/0000-0001-5097-3087
dc.authorwosidGüçlü, Hande/AAW-9756-2020
dc.authorwosidOzal, Sadık Altan/B-5123-2019
dc.authorwosidBirgul, Ramazan/AEP-5382-2022
dc.contributor.authorGuclu, Hande
dc.contributor.authorOzal, Sadik Altan
dc.contributor.authorGurlu, Vuslat Pelitli
dc.contributor.authorBirgul, Ramazan
dc.date.accessioned2024-06-12T11:17:47Z
dc.date.available2024-06-12T11:17:47Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose. To demonstrate the relation between optic neuritis (ON) and systemic inflammation markers as neutrophil lymphocyte ratio (N/L ratio), platelet count, mean platelet volume (MPV), and red cell distribution width (RDW) and furthermore to evaluate the utilization of these markers to predict the frequency of the ON episodes. Methods. Forty-two patients with acute ON and forty healthy subjects were enrolled into the study. The medical records were reviewed for age, sex, hemoglobin (Hb), Haematocrit (Htc), RDW, platelet count, MPV, white blood cell count (WBC), neutrophil and lymphocyte count, and neutrophil lymphocyte ratio (N/L ratio). Results. The mean N/L ratio, platelet counts, and RDW were significantly higher in ON group (p = 0.000, p = 0.048, and p = 0.002). There was a significant relation between N/L ratio and number of episodes (r = 0.492, p = 0.001). There was a statistically significant difference for MPV between one episode group and recurrent ON group (p = 0.035). Conclusions. Simple and inexpensive laboratory methods could help us show systemic inflammation and monitor ON patients. Higher N/L ratio can be a useful marker for predicting recurrent attacks.en_US
dc.identifier.doi10.1155/2015/758687
dc.identifier.issn2090-004X
dc.identifier.issn2090-0058
dc.identifier.pmid26060578en_US
dc.identifier.scopus2-s2.0-84929378583en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2015/758687
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24847
dc.identifier.volume2015en_US
dc.identifier.wosWOS:000354310500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofJournal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCell Distribution Widthen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectInflammatory Biomarkersen_US
dc.subjectDiabetic-Retinopathyen_US
dc.subjectDisease-Activityen_US
dc.subjectVisual Functionen_US
dc.subjectMarkeren_US
dc.subjectExperienceen_US
dc.subjectCountyen_US
dc.subjectTrialen_US
dc.titleElevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritisen_US
dc.typeArticleen_US

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