C-reactive protein and immunoglobulin-E response to coronary artery stenting in patients with stable angina

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dc.authoridAltun, Armagan/0000-0002-3233-8263
dc.authorwosidAltun, Armagan/ABB-5844-2020
dc.contributor.authorErdogan, O
dc.contributor.authorAltun, A
dc.contributor.authorGul, C
dc.contributor.authorOzbay, G
dc.date.accessioned2024-06-12T10:58:51Z
dc.date.available2024-06-12T10:58:51Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractRecent reports indicate that inflammatory mechanisms play a crucial role in the patho-genesis of atherosclerosis and neointimal proliferation as well as coronary restenosis. To provide baseline data for further Studies regarding stenting, restenosis and inflammatory response, we prospectively conducted a clinical study to investigate the time related response of plasma levels of immunoglobulin-E (IgE) and C-reactive protein (CRP) which are two different inflammatory markers mediated by different cytokines in stable patients who underwent elective coronary artery stenting. Thirteen consecutive stable patients who underwent coronary artery stenting were included in the Study. Levels of I-E and CRP were determined pre- and poststent implantation on four consecutive days and at the end of the first as well as third month. Levels of these two markers were gradually elevated on postprocedure days while reaching peak values oil the second and third days for IgE (initial 278 335 IU/mL vs peak 350 489 IU/mL, P = 0.01) and CRP (initial 0.5 +/- 0 mg/dL vs peak 2.7 +/- 3 mg/dL, P = 0.002), respectively. High levels gradually returned to baseline values determined at the end of the first and even third months after stent implantation implying an acute inflammatory reaction. Stent implantation seems not to cause any persistent and ongoing inflammatory response in the long term.en_US
dc.identifier.doi10.1536/jhj.44.593
dc.identifier.endpage600en_US
dc.identifier.issn0021-4868
dc.identifier.issue5en_US
dc.identifier.pmid14587641en_US
dc.identifier.scopus2-s2.0-10644227190en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage593en_US
dc.identifier.urihttps://doi.org/10.1536/jhj.44.593
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20208
dc.identifier.volume44en_US
dc.identifier.wosWOS:000186577700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJapan Heart Journal, Second Dept Of Internal Meden_US
dc.relation.ispartofJapanese Heart Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectImmunoglobulin Een_US
dc.subjectInflammationen_US
dc.subjectAtherosclerosisen_US
dc.subjectStenten_US
dc.subjectMast-Cellsen_US
dc.subjectMyocardial-Infarctionen_US
dc.subjectBalloon Angioplastyen_US
dc.subjectDiseaseen_US
dc.subjectActivationen_US
dc.subjectImplantationen_US
dc.subjectReleaseen_US
dc.subjectMitogenen_US
dc.titleC-reactive protein and immunoglobulin-E response to coronary artery stenting in patients with stable anginaen_US
dc.typeArticleen_US

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