Increased vein wall thickness in Behcet disease

dc.authorwosidSEYAHI, EMIRE/AAB-3576-2020
dc.authorwosidSeyahi, Emire/AAD-1769-2021
dc.contributor.authorSeyahi, Emire
dc.contributor.authorGjoni, Migena
dc.contributor.authorDurmaz, Emine Sebnem
dc.contributor.authorAkbas, Serkan
dc.contributor.authorSut, Necdet
dc.contributor.authorDikici, Atilla Suleyman
dc.contributor.authorMihmanli, Ismail
dc.date.accessioned2024-06-12T10:54:20Z
dc.date.available2024-06-12T10:54:20Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Lower extremity (LE) deep venous thrombosis (DVT) is the main feature of vascular involvement in Behcet disease (BD). We thought that vein wall thickness (VWT) could be a surrogate marker for venous inflammation and hence predict future vascular involvement. We assessed VWT in proximal LE veins in BD patients without DVT, BD patients with DVT, and healthy controls in a formal, masked protocol. Methods: We studied 50 (43 male and 7 female) BD patients with LE DVT (group 1), 50 (43 male and 7 female) BD patients without any vascular involvement (group 2), and 50 (43 male and 7 female) age- and sex-matched apparently healthy controls (group 3). Two radiologists blinded to the diagnosis of BD used ultrasound to measure VWT of common femoral vein, femoral vein, and great saphenous vein in both legs. Interobserver reliability was assessed using the intraclass correlation coefficient and Bland-Altman plots. Results: There was good agreement between the two observers. The mean VWT was significantly increased in both BD patients with LE DVT and those without apparent vascular involvement compared with the healthy controls, whereas those with LE DVT had the highest VWT. Conclusions: VWT of proximal deep and superficial LE veins is increased among the BD patients without any clinical and radiologic vascular involvement. This information, after prospective work, might be useful in management and elucidating disease mechanisms in vascular BD.en_US
dc.identifier.doi10.1016/j.jvsv.2018.11.006
dc.identifier.endpage+en_US
dc.identifier.issn2213-333X
dc.identifier.issue5en_US
dc.identifier.pmid30777674en_US
dc.identifier.scopus2-s2.0-85061619864en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage677en_US
dc.identifier.urihttps://doi.org/10.1016/j.jvsv.2018.11.006
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19004
dc.identifier.volume7en_US
dc.identifier.wosWOS:000491548200011en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal Of Vascular Surgery-Venous And Lymphatic Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet Diseaseen_US
dc.subjectLower Extremity Venous Thrombosisen_US
dc.subjectDoppler Ultrasounden_US
dc.subjectVein Wall Thicknessen_US
dc.subjectVascular Involvementen_US
dc.subjectThrombosisen_US
dc.subjectVenographyen_US
dc.titleIncreased vein wall thickness in Behcet diseaseen_US
dc.typeArticleen_US

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