Current Status of Radionuclide Renal Cortical Imaging in Pyelonephritis

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dc.authoridSarikaya, Ismet/0000-0002-1087-580X
dc.authorwosidSarikaya, Ismet/G-7881-2015
dc.contributor.authorSarikaya, Ismet
dc.contributor.authorSarikaya, Ali
dc.date.accessioned2024-06-12T11:13:31Z
dc.date.available2024-06-12T11:13:31Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPyelonephritis is an infection of the kidneys that is seen more commonly in children than the adults. Tc-99(m)-dimercaptosuccinic acid (Tc-99m-DMSA) scanning is a radionuclide imaging study to detect renal scarring after acute pyelonephritis (a late Tc-99m-DMSA scan) and also helps to diagnose acute pyelonephritis in febrile urinary tract infections (an acute Tc-99m-DMSA scan). Planar imaging in multiple views (posterior and bilateral posterior oblique) is generally used. Pinhole imaging with a high-resolution-collimator magnification of each kidney allows detection of smaller cortical defects. SPECT is optional. SPECT/CT is not recommended in children because it has a higher radiation exposure than routine Tc-99m-DMSA scans. The main limitations of Tc-99m-DMSA scanning include a relatively long waiting time after radiotracer injection, a long acquisition time, and a high radiation dose, which is particularly important in repeated studies on children and with the limited spatial resolution of y-cameras. Tc-99m-glucoheptonate is an alternative radiotracer when (99m)TcDMSA is not available. Radiotracers for dynamic renal functional imaging can grossly assess the renal cortex in the first few minutes of imaging. Ga-68-prostate-specific membrane antigen ligand (Ga-68-PSMA ligand) PET has the ability to provide images of normal renal cortex and demonstrate renal cortical defects from cysts. In this article, we assess the current status of renal cortical imaging and present Ga-68-PSMA ligand PET images. Ga-68-PSMA ligand provides excellent renal cortical images, and studies should be done to compare Ga-68-PSMA ligand PET with (99)mTc-DMSA scanning in renal diseases, particularly in pyelonephritis.en_US
dc.identifier.doi10.2967/jnmt.119.227942
dc.identifier.endpage312en_US
dc.identifier.issn0091-4916
dc.identifier.issn1535-5675
dc.identifier.issue4en_US
dc.identifier.pmid31182659en_US
dc.identifier.scopus2-s2.0-85075240419en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage309en_US
dc.identifier.urihttps://doi.org/10.2967/jnmt.119.227942
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23587
dc.identifier.volume47en_US
dc.identifier.wosWOS:000500933700012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSoc Nuclear Medicine Incen_US
dc.relation.ispartofJournal Of Nuclear Medicine Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRenal Cortical Imagingen_US
dc.subjectTc-99m-DMSAen_US
dc.subjectPyelonephritisen_US
dc.subjectGa-68-PSMA Liganden_US
dc.subjectPETen_US
dc.subjectDimercaptosuccinic Acid Scintigraphyen_US
dc.subjectMagnetic-Resonance Urographyen_US
dc.subjectProstate-Canceren_US
dc.subjectTc-99m-Dmsa Scintigraphyen_US
dc.subjectProcedure Guidelineen_US
dc.subjectHbed-Ccen_US
dc.subjectDiagnosisen_US
dc.subjectChildrenen_US
dc.subjectPet/Cten_US
dc.subjectSpecten_US
dc.titleCurrent Status of Radionuclide Renal Cortical Imaging in Pyelonephritisen_US
dc.typeArticleen_US

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