Community-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortality

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dc.authoridBİLGİÇ, HAYATİ/0000-0001-5208-3053
dc.authoridBilge, Ugur/0000-0002-5186-1092
dc.authoridErdem, Hakan/0000-0002-6265-5227
dc.authoridGungor, Gokay/0000-0003-2294-489X
dc.authoridONCUL, Mustafa Oral/0000-0002-1681-1866
dc.authoridtehli, gulden yilmaz/0000-0002-2186-492X
dc.authoridsenturk, ozgur/0000-0002-7776-109X
dc.authorwosidCilli, Aykut/C-7681-2016
dc.authorwosidsavasci, umit/AAA-1667-2021
dc.authorwosidBİLGİÇ, HAYATİ/AAC-8764-2021
dc.authorwosidInan, Asuman/IXW-7212-2023
dc.authorwosidInan, Asuman/D-5679-2014
dc.authorwosidturkan, hulya/AAE-4174-2021
dc.authorwosidBüyükkoçak, Ünase/JAZ-1016-2023
dc.contributor.authorCilli, Aykut
dc.contributor.authorErdem, Hakan
dc.contributor.authorKarakurt, Zuhal
dc.contributor.authorTurkan, Hulya
dc.contributor.authorYazicioglu-Mocin, Ozlem
dc.contributor.authorAdiguzel, Nalan
dc.contributor.authorGungor, Gokay
dc.date.accessioned2024-06-12T10:58:10Z
dc.date.available2024-06-12T10:58:10Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: The aims of this study are to identify factors predicting mortality in patients with chronic obstructive pulmonary disease (COPD) and community-acquired pneumonia (CAP) requiring intensive care unit (ICU) admission and to examine whether noninvasive ventilation treatment reduces mortality. Materials and Methods: An analysis was performed on data from patients with CAP hospitalized in the ICUs of 19 different hospitals in Turkey between October 2008 and January 2011. Predictors of mortality were assessed by both univariate and multivariate statistical analyses. Results: Two hundred eleven patients with COPD and CAP were included. The overall ICU mortality was 23.9%. Noninvasive ventilation treatment (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.03-0.49; P=.003), hypertension (OR, 0.13; 95% CI, 0.02-0.93; P=.042), bilateral infiltration (OR, 13.92; 95% CI, 2.94-65.84; P=.001), systemic corticosteroid treatment (OR, 0.19; 95% CI, 0.35-0.96; P=.045), length of ICU stay (OR, 0.65; 95% CI, 0.47-0.89; P=.007), and duration of invasive mechanical ventilation (OR, 1.11; 95% CI, 1.01-1.22; P=.032) were independent factors related to mortality. Conclusion: Noninvasive ventilation, hypertension, systemic corticosteroid treatment, and shorter ICU stay are associated with reduced mortality, whereas bilateral infiltration and longer duration of invasive mechanical ventilation are associated with increased risk of mortality in patients with COPD and CAP requiring ICU admission. (C) 2013 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.jcrc.2013.08.004
dc.identifier.endpage979en_US
dc.identifier.issn0883-9441
dc.identifier.issn1557-8615
dc.identifier.issue6en_US
dc.identifier.pmid24075301en_US
dc.identifier.scopus2-s2.0-84887408150en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage975en_US
dc.identifier.urihttps://doi.org/10.1016/j.jcrc.2013.08.004
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19969
dc.identifier.volume28en_US
dc.identifier.wosWOS:000326945100018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal Of Critical Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCommunity-Acquired Pneumoniaen_US
dc.subjectCOPDen_US
dc.subjectIntensive Care Uniten_US
dc.subjectAcute Respiratory-Failureen_US
dc.subjectPressure Support Ventilationen_US
dc.subjectNoninvasive Ventilationen_US
dc.subjectTract Infectionsen_US
dc.subjectCopd Patientsen_US
dc.subjectCorticosteroidsen_US
dc.subjectOutcomesen_US
dc.subjectHydrocortisoneen_US
dc.subjectPredictorsen_US
dc.subjectInhibitorsen_US
dc.titleCommunity-acquired pneumonia in patients with chronic obstructive pulmonary disease requiring admission to the intensive care unit: Risk factors for mortalityen_US
dc.typeArticleen_US

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