Effect of bladder distention on bladder base dose in gynaecological intracavitary high dose rate brachytherapy

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dc.authorwosidAdli, Mustafa/ABH-5809-2020
dc.contributor.authorAdli, M.
dc.contributor.authorGaripagaoglu, M.
dc.contributor.authorKocak, Z.
dc.date.accessioned2024-06-12T11:20:09Z
dc.date.available2024-06-12T11:20:09Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe purpose of this study was to assess the impact of bladder volume on bladder base doses during gynaecological intracavitary high dose rate (HDR) brachytherapy. 42 different intracavitary HDR brachytherapy applications (tandem and ovoid, 25; ovoid, 17) were performed in 41 patients treated for cervical (n=29) and endometrial (n=12) cancer. The International Commission on Radiation Units and Measurements (ICRU) bladder reference point (BRP) dose and doses of 17 points selected on the bladder base were calculated using planning orthogonal radiographs taken after applicator placement with 100 ml and 270 ml bladder volumes. The effect of bladder volume on ICRU BRP and bladder base maximum point (BBMP) doses were analysed for both types of applications. Median ICRU BRP doses (in percentage of prescription dose) were 36.2% (18.2-69.8%) and 40.0% (21.0-61.8%) for ovoid applications (p=0.13) and 34.9% (15.7-81.0%) and 33.8% (16.5-88.1%) for tandem and ovoid applications (p=0.48) in 100 ml and 270 ml bladder volumes, respectively. Median BBMP doses were 75.1% (33.8-141.0%) and 104.0% (62.8-223.0%) for ovoid applications (p < 0.001) and 116% (51.2-242.0%) and 124.0% (62.0-326%) for tandem and ovoid applications (p=0.018) in 100 ml and 270 ml bladder volumes, respectively. Although the BBMP dose significantly increases, the ICRU BRP dose does not change with increasing bladder volume in gynaecological intracavitary HDR brachytherapy. Increasing bladder volume increases bladder base maximum dose in intracavitary gynaecological brachytherapy.en_US
dc.identifier.doi10.1259/bjr/90233932
dc.identifier.endpage248en_US
dc.identifier.issn0007-1285
dc.identifier.issue975en_US
dc.identifier.pmid19064593en_US
dc.identifier.scopus2-s2.0-62449131189en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage243en_US
dc.identifier.urihttps://doi.org/10.1259/bjr/90233932
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25483
dc.identifier.volume82en_US
dc.identifier.wosWOS:000263791300011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBritish Inst Radiologyen_US
dc.relation.ispartofBritish Journal Of Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUterine Cervixen_US
dc.subjectRadiation-Therapyen_US
dc.subjectNormal Tissueen_US
dc.subjectCarcinomaen_US
dc.subjectDosimetryen_US
dc.subjectIrradiationen_US
dc.subjectMorbidityen_US
dc.subjectImplantsen_US
dc.subjectVolumesen_US
dc.subjectCanceren_US
dc.titleEffect of bladder distention on bladder base dose in gynaecological intracavitary high dose rate brachytherapyen_US
dc.typeArticleen_US

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