The role of inflammatory biomarkers in predicting primary acquired nasolacrimal duct obstruction and postoperative recurrence
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Nagoya Univ, Sch Med
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study aims to determine the relationship between systemic inflammatory biomarkers and primary acquired nasolacrimal duct obstruction and to evaluate whether they can be used as indicators in determining the risk of recurrence after dacryocystorhinostomy. This retrospective, comparative case series was conducted with 57 primary acquired nasolacrimal duct obstruction patients and 58 age-and gender-matched controls. All subjects underwent a complete ophthalmologic examination and complete blood count measurements. The mean neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune-inflammation index were significantly higher in patients with primary acquired nasolacrimal duct obstruction (p = 0.005, p = 0.01, and p = 0.003, respectively). In recurrent patients, the neutrophil-to-lymphocyte ratio was significantly higher than in those who did not develop a recurrence (p = 0.029). The area under the curve was determined as 0.775 (p = 0.029) for the neutrophil-to-lymphocyte ratio in predicting recurrence. The neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune-inflammation index levels were significantly higher in patients with primary acquired nasolacrimal duct obstruction compared to healthy controls. The neutrophil-to-lymphocyte ratio might be used as a simple and inexpensive indicator for predicting recurrence in patients with primary acquired nasolacrimal duct obstruction.
Açıklama
Anahtar Kelimeler
Inflammation, Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, Primary Acquired Nasolacrimal Duct Obstruction, Systemic Immune-Inflammation Index, To-Lymphocyte Ratio, Neutrophil/Lymphocyte Ratio, Lacrimal Sac, Dacryocystorhinostomy, Outcomes, Angle
Kaynak
Nagoya Journal Of Medical Science
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
85
Sayı
2
