The antimicrobial effect of various formulations obtained from Fomes fomentarius against hospital isolates

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dc.contributor.authorGedık, Gulsah
dc.contributor.authorDulger, Gorkem
dc.contributor.authorAsan, Hulya
dc.contributor.authorÖzyurt, Anıl
dc.contributor.authorAllı, Hakan
dc.contributor.authorAsan, Ahmet
dc.date.accessioned2024-06-12T10:04:57Z
dc.date.available2024-06-12T10:04:57Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe purpose of this study was to investigate the antimicrobial activity of formulations of F. fomentarius. The antimicrobial efficacy levels of extracts of F. fomentarius prepared from ethanol, water and of various formulations (emulsion, ointment, paste, cream and gel) were determined. For this purpose, the disk diffusion method was used to test the extracts for antimicrobial activity against hospital isolates including Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, vancomycin-resistant enterococci (VRE+), Escherichia coli, Candida krusei, C. albicans, C. tropicalis, C. guilliermondii and C. glabrata. Some standard antibiotics were used for comparison. The ointment formulation (No. 4) showed a good antimicrobial effect on bacteria compared to the antibiotics (9.6 - 16.1 mm.). The extracts were found to be more effective than the antibiotics against Candida species. Formulation No. 4 was considered to be more effective because of the protective nature of its cetyl alcohol and sodium lauryl sulfate (SLS) content . F. fomentarius ethanol extract, F. fomentarius water extract and gel formulation showed similar activity; however, other formulations (emulsion, paste, cream) were generally more effective due to the stabilizing effects of the polymers, oil and alcohols present in their preparations. The findings of this study establish the possibility of discovering new clinically effective antibiotic drugs and could be useful in understanding the relationship between traditional remedies and modern medicines.en_US
dc.identifier.doi10.30708mantar.535994
dc.identifier.endpage109en_US
dc.identifier.issn2147-6845
dc.identifier.issue2en_US
dc.identifier.startpage103en_US
dc.identifier.trdizinid397620en_US]
dc.identifier.urihttps://doi.org/10.30708mantar.535994
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/397620
dc.identifier.urihttps://hdl.handle.net/20.500.14551/13128
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMANTAR DERGİSİen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe antimicrobial effect of various formulations obtained from Fomes fomentarius against hospital isolatesen_US
dc.typeArticleen_US

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