The effects of antihypertensive agents on endometrial thickness in asymptomatic, hypertensive, postmenopausal women
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim of this study was to investigate, by using transvaginal ultrasonography, the possible effects on endometrial thickness of antihypertensive agents in asymptomatic postmenopausal women. Design: A prospective study in an outpatient menopause clinic of a university hospital. We included 288 postmenopausal women in this study, and we compared three groups of postmenopausal women as follows: (1) normotensive postmenopausal women, (2) hypertensive women treated with an antihypertensive drug (beta-blocker, non-beta-blocker, or beta-blocker plus non-p-blocker), and (3) untreated hypertensive women who had had hypertension for at least 1 year. Hypertensive women treated with a drug had been receiving treatment for 1 year. All women were interviewed and examined. Measurements of endometrial thickness were carried out by vaginal ultrasonography. Results: Sixty-two women (22%) were normotensive, and 226 (78%) of 288 women were hypertensive. Of the 226 women, 122 (54%) were receiving an antihypertensive drug. The mean (+/- SD) endometrial thicknesses in groups A, B, and C were 4.5 (+/- 1.3), 5.4 (+/- 1.5), and 6.4 (+/- 1.7) mm, respectively. Significant difference was obtained among the groups (P = 0.004). Conclusions: Our data indicate that the mean endometrial thickness is significantly greater in asymptomatic, hypertensive women receiving antihypertensive drugs than among untreated hypertensive and normotensive women.
Açıklama
Anahtar Kelimeler
Endometrial Thickness, Hypertension, Menopause, Antihypertensive Drugs, Growth-Factors, Cancer
Kaynak
Menopause-The Journal Of The North American Menopause Society
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
10
Sayı
4
