Effect of Painful Electrical Stimuli on Readiness Potential in the Human Brain
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The readiness potential (RP), which is a slow negative electrical brain potential that occurs before voluntary movement, can be interpreted as a measure of intrinsic brain activity originating from self-regulating mechanisms. Early and late components of the RP may indicate clinical-neurophysiological features such as motivation, preparation, intention, and initiation of voluntary movements. In the present study, we hypothesized that electrical pain stimuli modulate the preparatory brain activity for movement. The grand average evoked potentials were measured at sensory motor regions with EEG during an experimental protocol consisting of painful and nonpainful stimuli. Our results demonstrated that painful stimuli were preceded by an enhanced RP when compared to non-painful stimuli at the Cz channel (p < 0.05). Furthermore, the mean amplitude of the RP at the early phase was significantly higher for the painful stimuli when compared to the non-painful stimuli (p < 0.05). Our results indicate that electrical painful stimuli, which can be considered as an unpleasant and stressful condition, modulate the motor preparation at sensory motor regions to a different extent when compared to non-painful electrical stimuli. Since early component of the RP represents cortical activation due to anticipation of the stimuli and the allocation of attentional resources, our results suggest that painful stimuli may affect the motor preparation processes and the prediction of the movement at the cortical level.
Açıklama
Anahtar Kelimeler
Readiness Potential, Pain, Electroencephalography, Event-Related Potentials, Electrical Stimulation, Cerebral-Cortex, Motor Control, Movement, Thinking, Limb, Fear
Kaynak
Clinical Eeg And Neuroscience
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
53
Sayı
2
