Chitosan Effectiveness in End-to-End Vascular Anastomosis with Minimal Suture Technique
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer India
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background Vascular anastomosis, which is usually performed during complex surgical procedures such as transplantation and reconstruction, is a time-consuming and skilled practice. The aim of this study is to compare the vascular anastomosis technique made with minimal suture and chitosan with the traditional technique. Methods Twenty adult female Wistar Albino rats were randomly divided into two groups, the control group (n = 10) in which the traditional hand-sewn technique was applied and the chitosan group (n = 10) with the minimal suture technique. The duration of anastomosis, patency rates on the first and 28th days, and histopathology of the vessels on the 28th day were evaluated. Results The mean duration of anastomosis was calculated as 19.18 +/- 1.79 min in the control group and 11.30 +/- 0.97 min in the chitosan group. The difference between the two groups was statistically significant (p < 0.001). There was no significant difference between the patency rates of the control and chitosan groups, both within group (between the 1st and 28th days) and between the groups by day. In histopathological examination, especially in the control group, transmural damage, foreign body reactions due to the suture material, and granulomas were observed around the suture, while perivascular foreign body reactions were observed less frequently in the chitosan group compared to the control group. Conclusion We have shown that this new method of microvascular anastomosis is effective, easy to learn, and requires less time than conventional sutures. However, other studies should be conducted to prove the feasibility of this new technique and to prove its long-term success and results in the vessels.
Açıklama
Anahtar Kelimeler
Microvascular Anastomosis, Chitosan, Duration Of Anastomosis, Patency Rate, Rat, Microvascular Anastomosis
Kaynak
Indian Journal Of Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
85
Sayı
SUPPL 1
