Sarcopenia in Hodgkin's lymphoma evaluated with 18-FDG PET/CT, focus on age, performance, and treatment

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dc.authoridGökyer, Ali/0000-0002-1653-6155
dc.authoridBaysal, Mehmet/0000-0001-7681-4623
dc.authoridKirkizlar, Onur/0000-0001-7523-8599
dc.authoridKorkmaz, Ulku/0000-0002-7155-7610
dc.authoridDemirci, Ufuk/0000-0001-6923-1470
dc.authoridDemir, Ahmet Muzaffer/0000-0002-2073-5405
dc.authoridUmit, Elif/0000-0001-5589-3000
dc.authorwosidGökyer, Ali/AAQ-5700-2020
dc.authorwosidBaysal, Mehmet/E-9111-2018
dc.authorwosidKirkizlar, Onur/W-9594-2018
dc.authorwosidKorkmaz, Ulku/AAJ-4430-2020
dc.contributor.authorBas, Volkan
dc.contributor.authorUmit, Elif Gulsum
dc.contributor.authorKorkmaz, Ulku
dc.contributor.authorBaysal, Mehmet
dc.contributor.authorKaraman Gulsaran, Sedanur
dc.contributor.authorDemirci, Ufuk
dc.contributor.authorKirkizlar, Hakki Onur
dc.date.accessioned2024-06-12T11:03:21Z
dc.date.available2024-06-12T11:03:21Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractSarcopenia is defined as a progressive and generalized muscle disorder associated with certain physiological and pathological conditions. We aimed to evaluate the prevalence of sarcopenia in patients with HL using 18-fluoro deoxyglucose (FDG) PET/CT, which would provide a data of muscle mass with the CT compartment and also data of muscle metabolism with the 18-FDG compartment of the imaging modality. Fifty-nine patients diagnosed with HL were included in the study. PET/CT images before and after treatment were evaluated with regard to lumbar muscle mass and metabolism. Mean lumbar muscle evaluation with CT before treatment was 92, 40 HU, and after treatment was 89, 41 HU. Mean metabolic tumor volume (MTV) evaluated with FDG PET before treatment was 4, 13 mm(3)while after treatment was 4, 10 mm(3). The lumbar muscle mass in terms of HU which was evaluated with CT was observed to be decreased after treatment. Likewise, the metabolic evaluation was observed to be also decreased after treatment. Despite the decline in muscle mass after treatment in the whole group, this decline was particularly observed in the better initial performance group. In patients with BMI > 32, there was a significant decline in muscle mass. Abdominal nodal involvement was related with poorer muscle mass and quality. In HL care, particular attention should be given to patients who are younger and with better physical condition in terms of preserving the muscle reserves and preventing sarcopenia.en_US
dc.identifier.doi10.1007/s00520-020-05772-8
dc.identifier.endpage2480en_US
dc.identifier.issn0941-4355
dc.identifier.issn1433-7339
dc.identifier.issue5en_US
dc.identifier.pmid32929535en_US
dc.identifier.scopus2-s2.0-85090929913en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2475en_US
dc.identifier.urihttps://doi.org/10.1007/s00520-020-05772-8
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21615
dc.identifier.volume29en_US
dc.identifier.wosWOS:000569280600005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofSupportive Care In Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHodgkin's Lymphomaen_US
dc.subjectMuscleen_US
dc.subjectSarcopeniaen_US
dc.subject18-FDG PETen_US
dc.subjectCTen_US
dc.subjectIndependent Prognostic-Factoren_US
dc.subjectPathogenesisen_US
dc.titleSarcopenia in Hodgkin's lymphoma evaluated with 18-FDG PET/CT, focus on age, performance, and treatmenten_US
dc.typeArticleen_US

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