Effect of Six Months of Hemodialysis Treatment on Cognitive Function in Patients with End Stage Chronic Kidney Disease

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dc.contributor.authorKilinc, Vildan Coban
dc.contributor.authorUstundag, Sedat
dc.contributor.authorUstundag, Ayten
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T10:56:30Z
dc.date.available2024-06-12T10:56:30Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractOBJECTIVE: We aimed to investigate the prevalence of cognitive impairment (CI), its facilitating factors, and the effect of hemodialysis treatment on cognitive function (CF) in patients with stage V Chronic Kidney Disease (CKD). MATERIAL and METHODS: We investigated the prevalence of CI and its facilitating factors in 66 patients with CKD and analyzed the effect of hemodialysis on CF in 33 new hemodialysis patients. CF was evaluated in all patients by using the standardized mini mental test. RESULTS: CI was detected in 32% of our patients. We found a positive linear correlation between CI and lower educational status (p<0.001), elderly age (p=0.003), female gender (p<0.001), waist circumference (p=0.016), and urea levels (p=0.018). After 6 months of hemodialysis treatment, the CF score increased 0.5 points (p=0.092) and the rate of the patients with CI decreased to 27.3% from 39.4% (p=0.137). We observed that CI improves less with hemodialysis treatment in patients with high basal diastolic blood pressure (BP), (p=0.042). Although close to statistically significant, the improvement in CI was lower in patients with higher age (p=0.065), high basal mean BP (p=0.056) and basal systolic BP(r=0.269, p=0.135). CONCLUSION: Our findings suggest that evaluation of CI in CKD, elimination of its facilitating factors and not delaying hemodialysis when it is indicated decrease the morbidity and mortality due to CKD.en_US
dc.identifier.doi10.5262/tndt.2018.3089
dc.identifier.endpage188en_US
dc.identifier.issn1300-7718
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85047566273en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage178en_US
dc.identifier.urihttps://doi.org/10.5262/tndt.2018.3089
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19790
dc.identifier.volume27en_US
dc.identifier.wosWOS:000433118700012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurk Nefroloji Diyaliz Transplantasyon Dergisien_US
dc.relation.ispartofTurkish Nephrology Dialysis And Transplantation Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic Kidney Diseaseen_US
dc.subjectEnd Stage Chronic Kidney Diseaseen_US
dc.subjectHemodialysisen_US
dc.subjectCognitive Disfunctionen_US
dc.subjectMental-State-Examinationen_US
dc.subjectDialysis Patientsen_US
dc.subjectPeritoneal-Dialysisen_US
dc.subjectUnited-Statesen_US
dc.subjectImpairmenten_US
dc.subjectDementiaen_US
dc.subjectRisken_US
dc.subjectMortalityen_US
dc.subjectAdultsen_US
dc.subjectRecognitionen_US
dc.titleEffect of Six Months of Hemodialysis Treatment on Cognitive Function in Patients with End Stage Chronic Kidney Diseaseen_US
dc.typeArticleen_US

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