Subtle Systolic Dysfunction May Be Associated with the Tendency to Develop Diastolic Heart Failure in Patients with Preserved Left Ventricular Ejection Fraction

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dc.contributor.authorSueruecue, Hueseyin
dc.contributor.authorTath, Ersan
dc.contributor.authorDegirmenci, Ali
dc.contributor.authorOkudan, Selnur
dc.contributor.authorBoz, Hakki
dc.date.accessioned2024-06-12T10:59:31Z
dc.date.available2024-06-12T10:59:31Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: We looked for an answer to the question of whether diastolic heart failure (DHF) is a reality or all heart failures are systolic. Method: 300 cases (hypertensive, aged, obese, etc.), not being diagnosed DHF, with preserved left ventricular (LV) ejection fraction (EF) but having the tendency to develop DHF in future were examined. One hundred and eighty cases without exclusion criteria were selected. Cases were assigned to three groups according to noninvasively obtained pulmonary capillary wedge pressure (PCWP). Results: In cases with higher PCWP (> 10 mmHg), transmitral A velocity was increased (P < 0.001) and among the pulsed wave tissue Doppler imaging (pw-TDI) parameters Ea velocity was decreased (P < 0.001) and Ea-dt was prolonged (P < 0.005). In cases with lower PCWP (< 8 mmHg), transmitral E velocity was higher (P < 0.001). Furthermore, a more meaningful relationship was found between PCWP and systolic pw-TDI parameters. In all the groups, it was observed that Sa velocity was progressively decreased and Q-Sa interval was progressively prolonged as PCWP increased (for all the groups P < 0.046). Conclusion: The question whether DHF is a reality or all heart failures are systolic may be answered as follows. Subtle systolic dysfunction may be associated with the tendency to develop DHF in patients with preserved LV ejection fraction. As in systolic heart failure (EF < 45%), in patients with preserved systolic function (EF >= 45%), systolic and diastolic functions may impair together. The pw-TDI method may be more sensitive than standard echocardiography parameters in detection of systolic dysfunction in cases with preserved EF. (ECHOCARDIOGRAPHY, Volume 26, April 2009).en_US
dc.identifier.doi10.1111/j.1540-8175.2008.00824.x
dc.identifier.endpage370en_US
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue4en_US
dc.identifier.pmid19382943en_US
dc.identifier.scopus2-s2.0-63849281375en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage365en_US
dc.identifier.urihttps://doi.org/10.1111/j.1540-8175.2008.00824.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20479
dc.identifier.volume26en_US
dc.identifier.wosWOS:000264878600002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEchocardiography-A Journal Of Cardiovascular Ultrasound And Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiastolic Heart Failureen_US
dc.subjectPulsed-Wave Tissue Doppler Imagingen_US
dc.subjectCapillary Wedge Pressureen_US
dc.subjectTissue Doppler-Echocardiographyen_US
dc.subjectMyocardial-Infarctionen_US
dc.subjectFilling Pressuresen_US
dc.subjectMitral Annulusen_US
dc.subjectVelocityen_US
dc.subjectDiagnosisen_US
dc.subjectIndexen_US
dc.subjectWaveen_US
dc.titleSubtle Systolic Dysfunction May Be Associated with the Tendency to Develop Diastolic Heart Failure in Patients with Preserved Left Ventricular Ejection Fractionen_US
dc.typeArticleen_US

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