Screening of antimicrobial, antioxidant, antidiabetic activities, anatomical and morphological properties of Colchicum speciosum Steven (Colchicaceae)

Basit Öğe Kaydı
dc.authoridEksi Bona, Gulnur/0000-0002-6869-8703
dc.authoridGoger, Gamze/0000-0003-2978-5385
dc.authoridACAR SAHIN, AYDAN/0000-0002-5350-5534
dc.authoridTEKMAN, Enes/0000-0002-1226-7218
dc.authoridKARAKAYA, Songul/0000-0002-3268-721X
dc.authoridYUCA, Hafize/0000-0002-0857-4776
dc.authorwosidEksi Bona, Gulnur/AAH-4259-2020
dc.authorwosidGoger, Gamze/JCE-6911-2023
dc.authorwosidYuca, Hafize/O-7037-2019
dc.contributor.authorKarakaya, Songul
dc.contributor.authorGoger, Gamze
dc.contributor.authorBona, Gulnur Eksi
dc.contributor.authorYuca, Hafize
dc.contributor.authorAydin, Bilge
dc.contributor.authorTekman, Enes
dc.contributor.authorSahin, Aydan Acar
dc.date.accessioned2024-06-12T10:58:03Z
dc.date.available2024-06-12T10:58:03Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractColchicum speciosum Steven species is a perennial stemless plant. C. speciosum is a flowering herb native to mountainous regions of northern Turkey, the Caucasus, and northern Iran. It has been known as Vargit, Aci cigdem, Guz cigdemi. The present study reports the antimicrobial, antioxidant, alpha-amylase and alpha-glucosidase inhibitory activities of corm, leaf and flower methanol extracts, anatomical (light and electron microscopes) properties of root, corm, leaf, flowers and morphological characteristics of C. speciosum. Three different part of extracts C. speciosum were evaluated against E. coli ATCC 8739, S. aureus ATCC 6538, B. subtilis ATCC 19,659, C. albicans ATCC 10,231, C. krusei ATCC 14,243, and C. tropicalis ATCC 750. The most effective extract was found to be MeOH extract for corm and leaf against C. tropicalis ATCC 750 strain with MIC value 160 > mu g/mL. It has been investigated first time anatomy of the tepal, ovary, anther, filament of C. speciosum. Leaf extract was the highest phenolic component (78.61842 mu g GAE/mg extract). As a result of DPPH center dot and ABTS(center dot+) tests, it was determined that the leaf extract showed the best activity (IC50 = 6.568 mu g/mL and IC50 = 3.243 mu g/mL, respectively). Corm extract exhibited alpha-glucosidase inhibitory activity with an IC50 value of 21039 mu g/mL. This is the first study of the in vitro antimicrobial, antioxidant, antidiabetic activities, detailed anatomical and morphological properties of C. speciosum.en_US
dc.description.sponsorshipTurkish Scientific and Technical Research Council (TUBITAK)en_US
dc.description.sponsorshipBilge AYDIN and Enes TEKMAN would like to thank the scholarship along her postgraduate program provided by the Turkish Scientific and Technical Research Council (TUBITAK).en_US
dc.identifier.doi10.1007/s00709-022-01752-3
dc.identifier.endpage1506en_US
dc.identifier.issn0033-183X
dc.identifier.issn1615-6102
dc.identifier.issue6en_US
dc.identifier.pmid35262800en_US
dc.identifier.scopus2-s2.0-85125850404en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1493en_US
dc.identifier.urihttps://doi.org/10.1007/s00709-022-01752-3
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19919
dc.identifier.volume259en_US
dc.identifier.wosWOS:000766434600001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofProtoplasmaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColchicum Speciosumen_US
dc.subjectAntioxidanten_US
dc.subjectAntidiabeticen_US
dc.subjectAnatomicalen_US
dc.subjectMorphologicalen_US
dc.subjectExtractsen_US
dc.subjectL.en_US
dc.titleScreening of antimicrobial, antioxidant, antidiabetic activities, anatomical and morphological properties of Colchicum speciosum Steven (Colchicaceae)en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu