Dermoscopic Characteristics of Cutaneous Lupus Erythematosus According to Subtype, Lesion Location, Lesion Duration, and CLASI Score

dc.authoridGURSEL URUN, Yildiz/0000-0002-6137-8395
dc.authoridUrun, Mustafa/0000-0003-1272-8149
dc.contributor.authorUrun, Yildiz Gursel
dc.contributor.authorUrun, Mustafa
dc.contributor.authorDanisman, Mehmet Serif
dc.date.accessioned2024-06-12T10:59:39Z
dc.date.available2024-06-12T10:59:39Z
dc.date.issued2024
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: Dermoscopic findings are used to diagnose and evaluate disease activity in patients with cutaneous lupus erythematosus (CLE). Objectives: This study aimed to characterize the dermoscopic features of discoid LE (DLE) and LE tumidus (LET) by lesion duration and CLE Disease Area and Severity Index (CLASI) scores and to examine the dermoscopic findings of lesions in different locations in DLE patients. Methods: Dermoscopic findings (follicular features, perifollicular surface, interfollicular features, and vessel pattern) were assessed and lesion duration (<= 12 and >12 months) and CLASI scores (grouped as mild or moderate) were calculated. DLE lesion locations were categorized as, non-scalp, scalp and lip. Results: Forty-eight dermoscopic images from 35 DLE and 4 LET patients were analyzed. The most common dermoscopic findings in non-scalp DLE were follicular keratotic plugs (82.8%) and white scales (69%). In scalp DLE (n=9), the most common findings were absent follicular openings (77.8%), white structureless areas (77.8%), and perifollicular scaling (66.7%). All LET patients had pink-white background and linear vessels. Follicular plugs, peripheral pigmentation, and polymorphous vessels were lower in patients with mild CLASI activity than moderate activity (P = 0.036, 0.039, and 0.019, respectively). Fibrotic white dots, honeycomb pigment pattern, and blue-gray dots/globules were lower in those with mild CLASI damage scores than moderate damage (P = 0.010, 0.010, and 0.020, respectively). Peripheral pigmentation was more common in patients with lesion duration <= 12 months, while blue-gray dots/globules were more common with lesion durations >12 months. Conclusions: Certain dermoscopic features may facilitate the differential diagnosis of DLE and LET.en_US
dc.identifier.doi10.5826/dpc.1401a40
dc.identifier.issn2160-9381
dc.identifier.issue1en_US
dc.identifier.pmid38364410en_US
dc.identifier.scopus2-s2.0-85185759688en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.5826/dpc.1401a40
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20525
dc.identifier.volume14en_US
dc.identifier.wosWOS:001196706800021en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMattioli 1885en_US
dc.relation.ispartofDermatology Practical & Conceptualen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiscoid Lupus Erythematosusen_US
dc.subjectDermoscopyen_US
dc.subjectLupus Erythematosus Tumidusen_US
dc.subjectCutaneous Lupus Erythematosus Disease Area And Severity Indexen_US
dc.subjectOutcome Instrumenten_US
dc.subjectSeverity Indexen_US
dc.subjectDisease Areaen_US
dc.subjectClassificationen_US
dc.subjectDiagnosisen_US
dc.subjectTumidusen_US
dc.subjectManifestationsen_US
dc.subjectTrichoscopyen_US
dc.subjectDermatosesen_US
dc.subjectDamageen_US
dc.titleDermoscopic Characteristics of Cutaneous Lupus Erythematosus According to Subtype, Lesion Location, Lesion Duration, and CLASI Scoreen_US
dc.typeArticleen_US

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