Assessment of the relation between the neutrophil to lymphocyte ratio and severity of ischemic stroke in a large cohort

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dc.authoridakpinar, cetin kursad/0000-0001-9512-1048
dc.authoridYüksel, Burcu/0000-0003-3976-5564
dc.authoridKeskin, Ahmet Onur/0000-0002-2942-323X
dc.authoridBulbul, Nazli Gamze/0000-0001-8560-0774
dc.authorwosidCinar, Bilge Piri/AAA-5038-2021
dc.authorwosidakpinar, cetin kursad/A-1344-2016
dc.authorwosidYüksel, Burcu/GRX-4501-2022
dc.authorwosidAçıkgöz, Bilgehan/JAD-2339-2023
dc.authorwosidKeskin, Ahmet Onur/AAJ-2044-2021
dc.authorwosidGüllüoğlu, Halil/EGN-2421-2022
dc.authorwosidkorucu, osman/AAV-9585-2021
dc.contributor.authorPiri Cinar, Bilge
dc.contributor.authorKunt, Refik
dc.contributor.authorYuksel, Burcu
dc.contributor.authorGulluoglu, Halil
dc.contributor.authorSayilir, Idris
dc.contributor.authorCeliker Uslu, Sibel
dc.contributor.authorOzaydin Goksu, Eylem
dc.date.accessioned2024-06-12T11:17:44Z
dc.date.available2024-06-12T11:17:44Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim of study: The NLR is a simple and inexpensive parameter that is useful as a marker of subclinical inflammation. The purpose of this study was to investigate the clinical characteristics of patients diagnosed with acute cerebral ischemia at the time of initial evaluation in the emergency department. Patients and methods: The study was designed as a multicentre cross-sectional study of acute ischemic stroke patients. Neurological evaluations were assessed using the NIHSS and mRS. Evaluations included the results of patients' laboratory tests performed at the time of presentation to the emergency department. Results: Seven hundred and thirty-five ischemic stroke patients were included in the study. Stroke cases assessed by the mRS as mild or severe showed significant differences with respect to age, leukocyte counts, neutrophil counts, NLR, LDL cholesterol values, and serum glucose values (P = .001). When analysed using NIHSS, lymphocyte levels were significantly higher in very severe stroke cases compared with mild, moderate, and severe cases. NLR was also significantly higher in very severe stroke cases and severe stroke cases as compared with the mild and moderate stroke groups. Neurological evaluations assessed using the mRS showed a mild positive correlation with neutrophil and leukocyte count and a weak correlation with the NLR. Conclusion: The NLR exhibited a significant correlation with the results of the mRS and NIHSS. The NLR measured in the very early period was also significantly associated with clinical condition. These results suggest that high NLR values may be a marker of stroke' severity.en_US
dc.identifier.doi10.1111/ijcp.13955
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue4en_US
dc.identifier.pmid33342005en_US
dc.identifier.scopus2-s2.0-85099231129en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.13955
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24812
dc.identifier.volume75en_US
dc.identifier.wosWOS:000606823200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal Of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlood-Cell Subtypesen_US
dc.subjectNeutrophil/Lymphocyte Ratioen_US
dc.subjectInflammatory Responsesen_US
dc.subjectTerm Mortalityen_US
dc.subjectPredicten_US
dc.subjectDiseaseen_US
dc.subjectCountsen_US
dc.titleAssessment of the relation between the neutrophil to lymphocyte ratio and severity of ischemic stroke in a large cohorten_US
dc.typeArticleen_US

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