The effects of ritodrine and magnesium sulfate on maternal and fetal Doppler blood flow patterns in women with preterm labor

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dc.authorwosidSAYIN, N. CENK/A-5801-2018
dc.contributor.authorSayin, N. Cenk
dc.contributor.authorArda, Sezer
dc.contributor.authorVarol, Fusun G.
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T10:59:45Z
dc.date.available2024-06-12T10:59:45Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description21st European Congress of Perinatal Medicine -- SEP 10-13, 2008 -- Istanbul, TURKEYen_US
dc.description.abstractObjective: To determine the effects of ritodrine and magnesium sulfate on maternal-fetal blood flows. Study design: A total of 85 pregnant women between 26th and 36th weeks with preterm labor, and 83 healthy pregnant women were included. Patients in the study group were randomly assigned to receive either ritodrine (with the addition of verapamil) (n = 46) or magnesium sulfate (n = 39). Blood flow examinations on the umbilical artery (UA), middle cerebral artery (MCA), bilateral uterine arteries (Ut.A) and ductus venosus (DV) were performed before and 48 h after initiating therapy. Results: UA pulsatility index (PI) significantly differed in women receiving tocolysis compared to controls after 48 h. DV PI increased in women receiving MgSO(4), whereas it decreased in the ritodrine and control groups. Ut.A values did not significantly change after 48 h in the groups. In women between the 26th and 32nd weeks, UA, MCA and DV PI did not significantly change after 48 h in the three groups. However, in women between the 32nd and 36th weeks UA and MCA PI significantly differed in the treatment groups compared to controls after 48 h. DV PI increased in women receiving MgSO4, whereas it decreased in the ritodrine and control groups. Conclusions: MgSO4 and ritodrine affect blood flow patterns after 48 h in some maternal-fetal vessels. These effects on blood flow are particularly significant in women between 32nd and 36th weeks. The effects of both drugs on fetal and maternal Doppler flows seem similar, except the increased resistance to flow in DV in women receiving MgSO4. Crown Copyright (c) 2010 Published by Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejogrb.2010.05.021
dc.identifier.endpage54en_US
dc.identifier.issn0301-2115
dc.identifier.issue1en_US
dc.identifier.pmid20561741en_US
dc.identifier.scopus2-s2.0-77956615048en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage50en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2010.05.021
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20566
dc.identifier.volume152en_US
dc.identifier.wosWOS:000281936200010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal Of Obstetrics & Gynecology And Reproductive Biologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDoppleren_US
dc.subjectMagnesium Sulfateen_US
dc.subjectPretermen_US
dc.subjectRitodrineen_US
dc.subjectTocolysisen_US
dc.subjectVelocity Wave-Formsen_US
dc.subjectMaintenance Therapyen_US
dc.subjectTocolytic Therapyen_US
dc.subjectBetamethasoneen_US
dc.subjectNifedipineen_US
dc.subjectCirculationen_US
dc.subjectPregnancyen_US
dc.subjectArteryen_US
dc.subjectDexamethasoneen_US
dc.subjectHemodynamicsen_US
dc.titleThe effects of ritodrine and magnesium sulfate on maternal and fetal Doppler blood flow patterns in women with preterm laboren_US
dc.typeConference Objecten_US

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