Preventing Graft Loss Caused by Hematoma: Experimental Study

Basit Öğe Kaydı
dc.authoridTas, Suleyman/0000-0001-8874-3009
dc.authorwosidTas, Suleyman/B-3727-2014
dc.contributor.authorBenlier, Erol
dc.contributor.authorTas, Suleyman
dc.contributor.authorUsta, Ufuk
dc.date.accessioned2024-06-12T11:19:20Z
dc.date.available2024-06-12T11:19:20Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHematoma is a common reason for graft loss. This study was intended to investigate the effects of microporous polysaccharide hemospheres (MPH; Arista (R) AH; Medafor, Inc.) on graft survival, the effect of MPH on graft loss caused by hematoma, and the correlation between neutrophil accumulation and graft survival. A total of 35 adult male Wistar rats were separated into five groups of seven as follows: control 1, saline, MPH, control 2 (hematoma group), and MPH + hematoma. All graft dressing was removed on the fifth postoperative day and graft survival percentage measured. Histopathological and semiquantitative analysis, including inflammatory cell infiltration and subcutaneous inflammation based on neutrophil count, was performed. Graft survival significantly improved in the MPH group (97.86 +/- 1.676) compared with the control 1 (91.14 +/- 3.671; P = .004) and saline groups (91.57 +/- 4.791; P = .014). There was no significant increase in graft survival in the saline group compared with the control 1 group or in the MPH + hematoma group (19.57 +/- 14.707) compared with the control 2 group (20.71 +/- 16.869; P > .05). The neutrophil count was highest in the control 2 group (177.43 +/- 22.464) and significantly decreased in the MPH group (33. 71 +/- 8,674) compared with the control 1 group (66.14 +/- 5.872; P = .001) and the saline group (65.57 +/- 3.309; P = .001). There was no significant decrease in neutrophil count in the MPH + hematoma group (160.00 +/- 27.952) compared with the control 2 group (P > .05). It seems that MPH can increase the graft survival, and there is an inverse relationship between graft survival and neutrophil accumulation.en_US
dc.identifier.doi10.1097/BCR.0000000000000029
dc.identifier.endpage533en_US
dc.identifier.issn1559-047X
dc.identifier.issn1559-0488
dc.identifier.issue6en_US
dc.identifier.pmid24823329en_US
dc.identifier.scopus2-s2.0-84927785552en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage528en_US
dc.identifier.urihttps://doi.org/10.1097/BCR.0000000000000029
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25169
dc.identifier.volume35en_US
dc.identifier.wosWOS:000345159000022en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Burn Care & Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMicroporous Polysaccharide Hemospheresen_US
dc.subjectInduced Flap Necrosisen_US
dc.subjectIschemic Skin Flapsen_US
dc.subjectFree-Radicalsen_US
dc.subjectReperfusion Injuryen_US
dc.subjectCyclosporineen_US
dc.subjectNeutrophilsen_US
dc.subjectFixationen_US
dc.subjectSurgeryen_US
dc.subjectRatsen_US
dc.titlePreventing Graft Loss Caused by Hematoma: Experimental Studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu