GNB3 gene c.825C>T polymorphism and performance parameters in professional basketball players

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dc.authoridyucesir, ilker/0000-0002-0003-867X
dc.authorwosidBayraktar, Bulent/G-7534-2017
dc.authorwosidyucesir, ilker/E-4864-2019
dc.contributor.authorGulyasar, T.
dc.contributor.authorOzturk, L.
dc.contributor.authorSipahi, T.
dc.contributor.authorBayraktar, B.
dc.contributor.authorMetin, G.
dc.contributor.authorYucesir, I.
dc.contributor.authorSut, N.
dc.date.accessioned2024-06-12T11:02:34Z
dc.date.available2024-06-12T11:02:34Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThis study has been conducted to determine whether mean values of peak oxygen consumption (VO2peak), anaerobic test parameters and knee isokinetic test measurements are different among guanine nucleotide-binding protein, beta-3 (GNB3) genotype groups in a group of basketball players. Methods: Seventy-two healthy male (mean age, 22.9 +/- 5.3 years) basketball players from the first division of national league participated. We studied GNB3 gene c. 825C>T (rs5443) polymorphism, then divided the subjects into three groups as CC (n = 21), CT (n = 35), and TT (n = 16). Mean VO2peak, Wingate anaerobic test results, and isokinetic knee muscle strength measurements were compared among the genotype groups. Results: Mean VO2peak (60.1 +/- 3.9; 56.7 +/- 3.6; and 57.8 +/- 3.3, respectively, p < 0.01), mean anaerobic minimum power (5.1 +/- 0.4; 5.3 +/- 0.5; and 4.4 +/- 0.5 W/kg, respectively, p < 0.001), mean anaerobic power drop (57.0 +/- 6.2; 54.2 +/- 6.9; and 62.9 +/- 5.3%, respectively, p < 0.001) were significantly different among the study groups, CC, CT, and TT. Individuals with TT genotype exerted lower performance in terms of isokinetic knee muscle strength. Conclusion: The presence of 825T-allele may impair athletic performance and may serve as a genetic marker of low capacity for athletic performance in male basketball players.en_US
dc.identifier.doi10.1556/APhysiol.101.2014.2.6
dc.identifier.endpage184en_US
dc.identifier.issn0231-424X
dc.identifier.issn1588-2683
dc.identifier.issue2en_US
dc.identifier.pmid24901079en_US
dc.identifier.scopus2-s2.0-84902183875en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage176en_US
dc.identifier.urihttps://doi.org/10.1556/APhysiol.101.2014.2.6
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21333
dc.identifier.volume101en_US
dc.identifier.wosWOS:000337022600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAkademiai Kiado Zrten_US
dc.relation.ispartofActa Physiologica Hungaricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGenetic Polymorphismen_US
dc.subjectGNB3en_US
dc.subjectExercise Capacityen_US
dc.subjectVO2peaken_US
dc.subjectIsokinetic Knee Strengthen_US
dc.subjectBeta-3 Subunit Varianten_US
dc.subjectC825t Polymorphismen_US
dc.subject825t Alleleen_US
dc.subjectAssociationen_US
dc.subjectHypertensionen_US
dc.subjectMarathonen_US
dc.subjectObesityen_US
dc.titleGNB3 gene c.825C>T polymorphism and performance parameters in professional basketball playersen_US
dc.typeArticleen_US

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