Increased pulse wave velocity and shortened pulse wave propagation time in young patients with rheumatoid arthritis

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dc.authoridSOY, MEHMET/0000-0003-1710-7018
dc.authorwosidsoy, mehmet/AAD-5233-2020
dc.authorwosidYildiz, Mustafa/D-6892-2019
dc.contributor.authorYildiz, M
dc.contributor.authorSoy, M
dc.contributor.authorKurum, T
dc.contributor.authorOzbay, G
dc.date.accessioned2024-06-12T10:52:31Z
dc.date.available2024-06-12T10:52:31Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND: Rheumatoid arthritis (RA) is a systemic immune and inflammatory disease associated with excess cardiovascular morbidity and mortality. Pulse wave velocity (PWV) is an index of arterial stiffness and a marker of cardiovascular events. OBJECTIVE: To investigate arterial stiffness using carotid-femoral (aortic) PWV measurements in young patients with RA. PATIENTS AND METHODS: Eight patients (aged 21 to 34 years, seven women, mean RA duration 13.8+/-12.6 months) with RA according to the criteria of the American College of Rheumatology, and eight age- and sex-matched control subjects (aged 22 to 34 years, seven women) were recruited. Aortic PWV was determined using an automatic device, the Complior (Complior Colson, France), which allowed on-tine pulse wave recording and automatic calculation of PWV RESULTS: The carotid-femoral PWV, systolic blood pressure and heart rate were higher in young patients with RA than in sex- and age-matched control subjects (P=0.03, P=0.02 and P=0.002, respectively). In the young patients with RA, pulse wave propagation time between measurement sites was significantly shorter than in the control group (P=0.02). There were no significant differences in the sex, age, body mass index, waist to hip ratio, diastolic blood pressure, mean blood pressure or pulse pressure between the two groups (P=1.00, P=0.71, P=0.20, P=0.66, P=0.55, P=0.07 and P=0.11, respectively). CONCLUSION: The carotid-femoral PWV is increased and Pulse wave propagation time is decreased in young patients with RA. Measurements of carotid-femoral PWV may provide a simple and noninvasive technique for identifying patients at increased risk of vascular disease.en_US
dc.identifier.endpage1100en_US
dc.identifier.issn0828-282X
dc.identifier.issn1916-7075
dc.identifier.issue11en_US
dc.identifier.pmid15457305en_US
dc.identifier.scopus2-s2.0-4644315284en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1097en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18743
dc.identifier.volume20en_US
dc.identifier.wosWOS:000223968800004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofCanadian Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArterial Stiffnessen_US
dc.subjectPulse Wave Propagation Timeen_US
dc.subjectPulse Wave Velocityen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectHeart-Rateen_US
dc.subjectArterial Distensibilityen_US
dc.subjectRisken_US
dc.subjectDiseaseen_US
dc.subjectAtherosclerosisen_US
dc.subjectMortalityen_US
dc.titleIncreased pulse wave velocity and shortened pulse wave propagation time in young patients with rheumatoid arthritisen_US
dc.typeArticleen_US

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