The Utility of CONUT Score in Diffuse Large B Cell Lymphoma Patients

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dc.authoridKirkizlar, Onur/0000-0001-7523-8599
dc.authoridBaysal, Mehmet/0000-0001-7681-4623
dc.authoridDemirci, Ufuk/0000-0001-6923-1470
dc.authorwosidKirkizlar, Onur/W-9594-2018
dc.authorwosidBaysal, Mehmet/E-9111-2018
dc.contributor.authorBaysal, M.
dc.contributor.authorBas, V
dc.contributor.authorDemirci, U.
dc.contributor.authorGulsaran, S. K.
dc.contributor.authorUmit, E.
dc.contributor.authorKirkizlar, H. O.
dc.contributor.authorDemir, A. M.
dc.date.accessioned2024-06-12T10:58:26Z
dc.date.available2024-06-12T10:58:26Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Assessment of nutritional status is gaining more importance in cancer patients because nutritional status is associated with response to chemotherapy, side effects of cancer treatment and disease progression. Several studies that were performed on patients with solid malignancies have shown the clinical significance of CONUT score (Controlling nutritional status). Aims: Therefore we tried to show the utility of CONUT score in newly diagnosed Diffuse Large B Cell Lymphoma (DLBCL) patients which is the most frequently seen B Cell Lymphoma type. Methods: Data of the 81 patients diagnosed with DLBCL were retrospectively evaluated. The primary endpoint of our study was to evaluate and classify newly diagnosed DLBCL patients according to the CONUT score and secondary endpoint was to show any relationship with CONUT score and overall survival. Patients' demographics, treatment details, stages, extranodal involvements, the presence of bulky disease, response to treatment options and overall survivals were evaluated from medical recordings. Results: Univariate cox regression analysis CONUT score was associated with overall survival (HR: 2.34-95% CI: 1.55-3.24 P = 0.040). On multivariate Cox regression analysis model CONUT score >= 5 was found to be an independent prognostic factor for overall survival (HR: 4.96-95% CI: 1.77-13.97- P = 0.002). Conclusion: The value of obtaining nutritional status in cancer patients is underestimated and CONUT score is simple, easily applicable and in our opinion is going to fill the gap especially in DLBCL patients.en_US
dc.identifier.doi10.4103/njcp.njcp_429_20
dc.identifier.endpage1199en_US
dc.identifier.issn1119-3077
dc.identifier.issn2229-7731
dc.identifier.issue8en_US
dc.identifier.pmid34397030en_US
dc.identifier.scopus2-s2.0-85113430780en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1194en_US
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_429_20
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20070
dc.identifier.volume24en_US
dc.identifier.wosWOS:000686177700014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal Of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectControlling Nutritional Status Scoreen_US
dc.subjectDiffuse Large B Cell Lymphomaen_US
dc.subjectPrognosisen_US
dc.subjectPrognostic Nutritional Indexen_US
dc.subjectChemotherapy Plus Rituximaben_US
dc.subjectClinical-Significanceen_US
dc.subjectRisk Indexen_US
dc.subjectPredictoren_US
dc.subjectPooren_US
dc.subjectChopen_US
dc.subjectHypoalbuminemiaen_US
dc.subjectLymphopeniaen_US
dc.subjectSurvivalen_US
dc.titleThe Utility of CONUT Score in Diffuse Large B Cell Lymphoma Patientsen_US
dc.typeArticleen_US

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