Evaluation of Patients with Acute Viral Hepatitis

Küçük Resim Yok

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Galenos Yayincilik

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Thirty-eight patients with acute viral hepatitis were admitted to Trakya University Hospital from January 2001 to June 2004. These patients were evaluated according to their complaints, clinical findings and laboratory results, retrospectively. Twenty-one (55.3%) of the patients were acute viral hepatitis A; 17 (44.7%) were acute viral hepatitis B. In SPSS software, clinical findings were evaluated with Fisher's exact test and laboratory results were evaluated in independent groups with non parametric t-test. The symptoms of the patients were weakness (85.7%, 88.2%), jaundice (85.7%, 88.2%), anorexia (76.2%, 52.9%), nausea (76.2%, 64.7%), darkening of urine color (71.4%, 76.5%), vomitting (57.1%, 41.2%) in hepatitis A and B, respectively. the signs of the patients were icterus (95.2%, 100%), hepatomegaly (28.6%, 47.1%), splenomegaly (9.5%, 23.5%) in hepatitis A and B, respectively. The-re was no significant difference in clinical findings. The mean age was 21.5 in hepatitis A and 33 in hepatitis B. In hepatitis A, mean aspartate aminotransferase (AST) value was 1345 U/L and mean alanine aminotransferase (ALT) value was 1910 U/L; in hepatitis B mean AST value was 1475 U/L, mean ALT was 2445 U/L. The level of ALT in hepatitis B cases was significantly higher than hepatitis A. In hepatitis A, mean total bilirubin value was 5.9 mg/dL, direct bilirubin was 3.5 mg/dL. In hepatitis B, total bilirubin was found 11.4 mg/dL, direct bilirubin was 7.7 mg/dL. Bilirubin levels in hepatitis B cases were significiantly higher than hepatitis a cases. There was no significant difference between two groups in the other laboratory findings. Although ALT and bilirubin levels in hepatitis B is higher than hepatitis A, the etiology of acute viral hepatitis can not be determined with the initial clinical and laboratory results.

Açıklama

Anahtar Kelimeler

Hepatitis A, Hepatitis B, Clinical Findings, Laboratory Results

Kaynak

Viral Hepatit Dergisi-Viral Hepatitis Journal

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

10

Sayı

3

Künye