The Effect of Admission Blood Pressure on the Prognosis of Patients with Intracerebral Hemorrhage That Occurred during Treatment with Aspirin, Warfarin, or No Drugs

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dc.contributor.authorBalci, Kemal
dc.contributor.authorUtku, Ufuk
dc.contributor.authorAsil, Talip
dc.contributor.authorCelik, Yahya
dc.contributor.authorTekinaslan, Ilkay
dc.contributor.authorIr, Nasif
dc.contributor.authorUnlu, Ercument
dc.date.accessioned2024-06-12T11:07:14Z
dc.date.available2024-06-12T11:07:14Z
dc.date.issued2012
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground. Hypertension is the most important modifiable risk factor for intracerebral hemorrhage (ICH), but blood pressure (BP) management during the acute phase of ICH is still controversial. Approximately one-fourth of ICHs occur during treatment with warfarin or aspirin. Aim. This study was designed to determine the effect of admission BP on the early prognosis of ICH patients by dividing them into three groups (warfarin, aspirin, and no drugs). Methods. Three hundred and sixty-nine patients with supratentorial ICH were divided into three groups according to medication. Each group was evaluated in terms of prognosis and the risk for mortality based on the modified Rankin Scale (mRS) score at discharge (good prognosis: mRS <= 3; poor prognosis: mRS > 3). The effect of admission BP on prognosis was evaluated for each group. Results. The inhospital mortality rate was 72% for ICH patients treated with warfarin, 41.6% for ICH patients treated with aspirin, and 35% for ICH patients treated with no drugs. Admission mean arterial blood pressure (MABP) values were higher in patients with poor prognosis compared with patients with good prognosis for the aspirin (P = .002) and no-drug (P = .001) groups, but not in the warfarin (P = .067) group. Conclusion. A high MABP at admission was found to be an independent predictor of poor prognosis for ICH patients treated with aspirin or with no drugs, but not for ICH patients treated with warfarin.en_US
dc.identifier.doi10.3109/10641963.2011.601380
dc.identifier.endpage124en_US
dc.identifier.issn1064-1963
dc.identifier.issue2en_US
dc.identifier.pmid21967033en_US
dc.identifier.scopus2-s2.0-84859586403en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://doi.org/10.3109/10641963.2011.601380
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21963
dc.identifier.volume34en_US
dc.identifier.wosWOS:000302562900007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofClinical And Experimental Hypertensionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntracerebral Hemorrhageen_US
dc.subjectBlood Pressureen_US
dc.subjectPrognosisen_US
dc.subjectMortalityen_US
dc.subjectAcute Strokeen_US
dc.subjectIndependent Predictoren_US
dc.subject30-Day Mortalityen_US
dc.subjectManagementen_US
dc.subjectHypertensionen_US
dc.subjectStatementen_US
dc.subjectSurvivalen_US
dc.subjectTherapyen_US
dc.subjectDeathen_US
dc.subjectRisken_US
dc.titleThe Effect of Admission Blood Pressure on the Prognosis of Patients with Intracerebral Hemorrhage That Occurred during Treatment with Aspirin, Warfarin, or No Drugsen_US
dc.typeArticleen_US

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