Impact of smoking on disease severity in patients with plaque type psoriasis

dc.authoridözgöztaşı, orhan/0000-0001-7192-0398;
dc.authorwosidözgöztaşı, orhan/AAH-1425-2020
dc.authorwosidKorkmaz, Selma/JRX-3713-2023
dc.authorwosidKorkmaz, Selma/W-4142-2017
dc.contributor.authorKayiran, Nuriye
dc.contributor.authorKorkmaz, Selma
dc.contributor.authorOzgoztasi, Orhan
dc.date.accessioned2024-06-12T11:13:05Z
dc.date.available2024-06-12T11:13:05Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and Design: Psoriasis is a chronic enflammatory systemic disease involving skin, scalp, nails and joints and is characterized by remission and activation periods. Although the etiopathogenesis of psoriasis has not been fully elucidated, many genetic and environmental factors are believed to have a role in the development of the disease. Obesity, smoking, family history of psoriasis, repetitive physical traumas and stress are the factors thought to affect the severity and progress of the disease. In this study, we aimed to investigate the effects of smoking on the clinical severity of psoriasis in patients with chronic plaque psoriasis. Materials and Methods: Three hundred outpatients with chronic plaque-type psoriasis were enrolled in the study. Data on age, gender, family history, smoking history, educational status, history of chronic illness, and psoriasis area severity index (PASI) scores were recorded for each patient. The effects of these factors on PASI were evaluated. Results: Current smokers, never smokers and former smokers were compared in terms of disease severity. The median PASI values of current smokers and never smokers were compared. The mean PASI value was statistically significantly higher in smokers (p=0.049). In multiple logistic regression analysis, it was detected that the risk of moderate and severe disease increased by male sex 2 times, by family history 2.3 times, and by smoking period above 20 years, 10 times. In smokers of more than 1 pack a day, this risk further increased. Conclusion: On the basis of these data, it may be concluded that smoking affects the severity of disease significantly. In addition to amount of daily cigarette consumption, smoking period was shown to have an effect on the severity of disease. Elimination of risk factors such as smoking, which appears to increase the severity of diseases, may be helpful in the management of psoriasis.en_US
dc.identifier.doi10.4274/turkderm.26086
dc.identifier.endpage22en_US
dc.identifier.issn1019-214X
dc.identifier.issn1308-6294
dc.identifier.scopus2-s2.0-84962291025en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage19en_US
dc.identifier.urihttps://doi.org/10.4274/turkderm.26086
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23411
dc.identifier.volume49en_US
dc.identifier.wosWOS:000369630900005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives Of Dermatology And Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPsoriasisen_US
dc.subjectSmokingen_US
dc.subjectPsoriasis Area Severity Indexen_US
dc.subjectRisk-Factorsen_US
dc.subjectAlcoholen_US
dc.titleImpact of smoking on disease severity in patients with plaque type psoriasisen_US
dc.typeArticleen_US

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