Adequacy of surgical margins, re-excision, and evaluation of factors associated with recurrence: a retrospective study of 769 basal cell carcinomas

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dc.authoridSarikaya Solak, Sezgi/0000-0002-8572-8249
dc.authoridGURSEL URUN, Yildiz/0000-0002-6137-8395
dc.authoridUrun, Mustafa/0000-0003-1272-8149
dc.authorwosidSarikaya Solak, Sezgi/A-4789-2016
dc.contributor.authorUrun, Yildiz Gursel
dc.contributor.authorCan, Nuray
dc.contributor.authorBagis, Merve
dc.contributor.authorSolak, Sezgi Sarikaya
dc.contributor.authorUrun, Mustafa
dc.date.accessioned2024-06-12T10:54:13Z
dc.date.available2024-06-12T10:54:13Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Achieving adequate surgical margins and preventing recurrence are important in the treatment of basal cell carcinoma (BCC). Objectives: The objectives of this study were to evaluate the adequacy of surgical margins and the re-excision rates in patients with primary BCC who underwent standard surgical treatment using our proposed algorithm and to define the risk factors in patients with recurrent BCC. Methods: The medical records of patients who were histopathologically diagnosed with BCC were reviewed. An algorithm created based on previous literature was used to determine the distribution of optimal surgical margins adequacy and re-excision rates. Results: Statistically significant differences were observed between the cases with and without recurrence in age at diagnosis (p = 0.004), tumor size (p = 0.023), tumor location in the H zone of the face (p = 0.005), and aggressive histopathological subtype (p = 0.000). When the tumors were evaluated for adequacy of deep and lateral surgical margins and re-excision rates, higher rates of adequate excision (457 cases, 68.0%) and re-excision (43 cases, 33.9%) were noted for tumors in the H or M zone. Study limitations: Inadequate follow-up of newly diagnosed patients in terms of recurrence and metastasis and the retrospective application of our proposed algorithm are the limitations of the present study. Conclusions: Our results showed that if BCC was detected at an early age and at an early stage, recurrence was lower. The H and M zones were the regions with the highest rates of optimal surgical outcomes. (c) 2023 Sociedade Brasileira de Dermatologia. Published by Elsevier Espan & SIM;a, S.L.U. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.identifier.doi10.1016/j.abd.2022.07.005
dc.identifier.endpage459en_US
dc.identifier.issn0365-0596
dc.identifier.issn1806-4841
dc.identifier.issue4en_US
dc.identifier.pmid36934062en_US
dc.identifier.scopus2-s2.0-85150367340en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage449en_US
dc.identifier.urihttps://doi.org/10.1016/j.abd.2022.07.005
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18971
dc.identifier.volume98en_US
dc.identifier.wosWOS:001027045400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAnais Brasileiros De Dermatologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBasal Cellen_US
dc.subjectMargins Of Excisionen_US
dc.subjectNeoplasm Metastasisen_US
dc.subjectRisk Factoren_US
dc.subjectRecurrenceen_US
dc.subjectRisk-Factorsen_US
dc.subjectIncomplete Excisionen_US
dc.subjectEpidemiologyen_US
dc.subjectManagementen_US
dc.subjectUpdateen_US
dc.subjectCanceren_US
dc.titleAdequacy of surgical margins, re-excision, and evaluation of factors associated with recurrence: a retrospective study of 769 basal cell carcinomasen_US
dc.typeArticleen_US

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