Distribution of GABPB1 gene rs7181866 polymorphism in rugby players

Basit Öğe Kaydı
dc.contributor.authorYilmaz, Ozlem Ozge
dc.contributor.authorPolat, Tolga
dc.contributor.authorEken, Basak Funda
dc.contributor.authorTuna, Gokhan
dc.contributor.authorAslan, Beste Tacal
dc.contributor.authorUlucan, Korkut
dc.date.accessioned2024-06-12T10:52:47Z
dc.date.available2024-06-12T10:52:47Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractNuclear respiration factor 2 is an important respiratory factor for cellular metabolism formed by polypeptides produced by the GA binding protein transcription factor subunit alpha (GABPA) and GA binding protein transcription factor subunit beta 1 (GAPPB1) genes. A functional polymorphism on the GABPB1 gene (rs7181866, G/A) alters the cellular respiration metabolism by affecting the protein dynamics. In this context, here, we examined the distribution of GABPB1 rs718186 polymorphism in professional rugby players to see its relationship with their stamina. Twelve rugby players participated in the study. Genotyping was performed by Real-Time PCR after DNAs were isolated from blood cells using commercially available isolation kits. In our cohort, the AA genotype and the A allele were superior to the AG and GG genotypes and the G allele. There was no statistically significant difference in terms of Genotypes (p=0.9027) and allelic groups (p=0.6948) in the athlete and control groups. Studies have revealed the relationship between endurance characteristics of athletes and rs7181866 AA genotype and A allele. These studies will be an important data source for future studies in sports genetics and GAPPB1 analysis.en_US
dc.identifier.doi10.56042/ijeb.v61i12.4003
dc.identifier.endpage932en_US
dc.identifier.issn0019-5189
dc.identifier.issn0975-1009
dc.identifier.issue12en_US
dc.identifier.startpage929en_US
dc.identifier.urihttps://doi.org/10.56042/ijeb.v61i12.4003
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18830
dc.identifier.volume61en_US
dc.identifier.wosWOS:001112537100006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherNatl Inst Science Communication-Niscairen_US
dc.relation.ispartofIndian Journal Of Experimental Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAthletic Performanceen_US
dc.subjectEnduranceen_US
dc.subjectNuclear Respiration Factoren_US
dc.subjectSport Geneticsen_US
dc.subjectMitochondrial Biogenesisen_US
dc.subjectPerformanceen_US
dc.subjectAssociationen_US
dc.titleDistribution of GABPB1 gene rs7181866 polymorphism in rugby playersen_US
dc.typeArticleen_US

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