PROGNOSTIC FACTORS AND TREATMENT RESULTS IN LARYGEAL CARCINOMA: DEPARTMENT OF RADIATION ONCOLOGY OF TRAKYA UNIVERSITY MEDICAL SCHOLL EXPERIENCE

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dc.authorwosidUygun, Kazim/AAG-7880-2022
dc.authorwosidUygun, Kazim/AFL-7917-2022
dc.contributor.authorCaloglu, Murat
dc.contributor.authorYurut Caloglu, Vuslat
dc.contributor.authorUzal, Cem
dc.contributor.authorKaragol, Hakan
dc.contributor.authorTokatli, Fusun
dc.contributor.authorUygun, Kazim
dc.date.accessioned2024-06-12T11:07:28Z
dc.date.available2024-06-12T11:07:28Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: To review the Department of Radiation Oncology of Trakya University Medical School experience in the treatment of laryngeal carcinoma and to evaluate the different factors affecting locoregional control. Methods and Material: We reviewed the records of 78 consecutive patients were treated for laryngeal carcinoma between July 1999 and November 2004. There were 74 men and 4 women, with a median age of 58 years (range, 34-80 years). Forty-two patients had T4 lesions, and 20 had T3 lesions; 32 had NO, 15 had N1, 27 had N2, and 2 had Nx disease. Surgery was the primary treatment modality in 34 patients. Twenty-six patients had RT alone, or chemotherapy combined with RT. Eighteen patients applied with locoregional or distant recurrent disease and they were given salvage or palliative treatment. x2 statistics were employed to identify significant factors for LRC. Results: The median follow-up was 18 months (range, 4-54 months). Twelve patients relapsed, of which 9 (26.5 %) locoregional failures among 34 patients of postoperative radiotherapy group. Significant prognostic factors for locoregional recurrence on univariate analysis were performance status, and surgical margin. Nine of 26 (34.6 %) patients relapsed and all of them had locoregional failures in primary radiotherapy group. Significant prognostic factors for these patients were primary tumor site, overall stage, T stage, and N stage. Conclusion: Radiotherapy is effective in the treatment of laryngeal carcinoma. The identification of prognostic factors for locoregional recurrence could help to determine more effective treatment strategies.en_US
dc.identifier.endpage26en_US
dc.identifier.issn1300-7467
dc.identifier.issue1en_US
dc.identifier.startpage20en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22058
dc.identifier.volume20en_US
dc.identifier.wosWOS:000439247300003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Onkoloji Dergisi-Turkish Journal Of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLaryngeal Carcinomaen_US
dc.subjectRadiotherapyen_US
dc.subjectChemotherapyen_US
dc.subjectLoco-Regional Controlen_US
dc.subjectPrognostic Factorsen_US
dc.titlePROGNOSTIC FACTORS AND TREATMENT RESULTS IN LARYGEAL CARCINOMA: DEPARTMENT OF RADIATION ONCOLOGY OF TRAKYA UNIVERSITY MEDICAL SCHOLL EXPERIENCEen_US
dc.typeArticleen_US

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