The Effect of Protocol Guided Therapy to Severe Sepsis Mortality

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dc.authoridDikmen, Yalim/0000-0002-3122-5099;
dc.authorwosidDikmen, Yalim/G-6301-2012
dc.authorwosidDemirkiran, Oktay/D-4129-2019
dc.contributor.authorCopuroglu, Elif
dc.contributor.authorDikmen, Yalim
dc.contributor.authorDemirkiran, Oktay
dc.contributor.authorUtku, Tughan
dc.contributor.authorUrkmez, Seval
dc.date.accessioned2024-06-12T11:14:03Z
dc.date.available2024-06-12T11:14:03Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: The aim of our study was to investigate the effect of protocol-based therapy to the severe sepsis patients and to investigate the accordance with this protocol. Patients and Methods: According to the evidence based guideline therapy, 'Severe Sepsis Treatment Protocol' was evaluated in order to lead the therapy of severe sepsis and septic shock patients. Before starting to our study, all the intensive care stuffs were informed about the diagnostic criteria for sepsis and severe sepsis (Appendix 1). One hundred and forty eight severe sepsis and septic shock patients that underwent therapy between 2003-2004 at Sadi Sun Intensive Care Unit were investigated retrospectively to create our Retrospective Group (RG). The study group was performed on 62 severe sepsis patients, that had underwent 'Severe Sepsis Treatment Protocol' based therapy at the same intensive care unit, between June 2005- June 2006 named as Prospective Group (PG). The mortality rate was compared between two groups. The treatment compliances at the first 6 hours and 24 hours has been evaluated in group PG. Results: Mortality rate was lower in PG, but this difference was not statistically significant (p>0.204). The accordance to the protocol of the first 6 hour therapy bundle and the 24 hour therapy bundle was found % 84.46 and % 59.54 respectively. Conclusion: Our study shows that, protocol-based therapy decreases the mortality in severe sepsis and septic shock patients.en_US
dc.identifier.doi10.4274/tybdd.09.17
dc.identifier.endpage98en_US
dc.identifier.issn2146-6416
dc.identifier.issn2147-267X
dc.identifier.issue3en_US
dc.identifier.startpage90en_US
dc.identifier.urihttps://doi.org/10.4274/tybdd.09.17
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23787
dc.identifier.volume9en_US
dc.identifier.wosWOS:000422264400003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of The Turkish Society Of Intensive Care-Turk Yogun Bakm Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSepsisen_US
dc.subjectProtocolen_US
dc.subjectMortalityen_US
dc.subjectGoal-Directed Therapyen_US
dc.subjectIntensive-Care-Uniten_US
dc.subjectSeptic Shocken_US
dc.subjectGolden Houren_US
dc.subjectImplementationen_US
dc.subjectEpidemiologyen_US
dc.subjectGuidelinesen_US
dc.subjectManagementen_US
dc.subjectStatesen_US
dc.titleThe Effect of Protocol Guided Therapy to Severe Sepsis Mortalityen_US
dc.typeArticleen_US

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