Epilepsy and Thyroid Hormones
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kare Publ
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The nervous and endocrine systems are 2 important related systems. Thyroid hormones, in particular, bind to the nuclear receptors of neuronal and glial cells, which affects migration, myelination, and synaptogenesis, and contributes to the development and differentiation of the nervous system. Changes in thyroid hormone levels during the early periods of life can cause serious and permanent damage to the nervous system. Although the exact mechanism is unknown, thyroid hormones interfere with the excitatory and inhibitory neurons and are thought to alter the cerebral epileptogenic threshold. Therefore, thyroid hormones may play a role in the pathogenesis of epilepsy.
Açıklama
Anahtar Kelimeler
Epilepsy, Epileptogenesis, Thyroid Hormones, Temporal-Lobe Epilepsy, Adult-Rat Brain, Mitochondrial Dysfunction, Antiepileptic Drugs, Oxidative Stress, Cerebral-Cortex, Nervous-System, Deficient Mice, Receptor, Cells
Kaynak
Epilepsi
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
24
