Can 68Ga-DOTA Peptides Be Potential Radiotracers for PET Imaging of the Spleen?

Küçük Resim Yok

Tarih

2018

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Soc Nuclear Medicine Inc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

On radionuclide somatostatin receptor imaging studies, the spleen shows high physiologic uptake. Reducing the intensity of the image settings helps to better assess the distribution of radiotracer in the spleen. In our routine studies, we incidentally recognized that Ga-68-DOTANOC PET provides higher-resolution splenic images than In-111-octreotide SPECT. Autoradiography and immunohistochemistry studies have shown that somatostatin receptors are located mainly in the red pulp of the spleen. The distribution of Ga-68-DOTANOC in the spleen appears to correlate with the distribution of red pulp. In this article, we present Ga-68-DOTANOC PET/CT spleen images of our patients.

Açıklama

Anahtar Kelimeler

Spleen, Somatostatin Receptor, Red Pulp, Ga-68-DOTANOC, PET/CT, Somatostatin Receptors, Neuroendocrine Tumors, Lymphoid Organs, Localization, Scintigraphy

Kaynak

Journal Of Nuclear Medicine Technology

WoS Q Değeri

N/A

Scopus Q Değeri

Q3

Cilt

46

Sayı

2

Künye