Evaluation of Clinical and Laboratory Features of Epstein-Barr Virus-Associated Acute Infectious Mononucleosis in Children

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Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Aves Yayincilik, Ibrahim Kara

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objectives: The various symptoms of infectious mononucleosis associated with Epstein-Barr virus may confuse physicians in differential diagnosis. The aim of this study is to evaluate the clinical and laboratory findings of this disease in symptomatic children. Patients and Methods: This study was retrospectively performed on 52 cases (31 boys, 21 girls; mean age 5.4 +/- 3.4 years; range 1 to 13 years) with acute Epstein-Barr virus infection. The clinical and laboratory findings were evaluated according to admission time after initial complaints (<= 5/>5 days) and the age groups of the cases (<= 2/>2 years). Results: The major symptoms were fever, lymphadenopathy and tonsillopharyngitis in the classical triad. Moreover, atypical cases who had ascites, arthritis and severe abdominal pain were defined. No case had a poor prognosis. The most frequent laboratory finding was lymphocytosis. While the major symptoms were more frequent in the group admission time <= 5 days, the count of atypical lymphocyte were higher in the group admission time > 5 days. However, these differences could not be defined between age groups. Conclusion: Infectious mononucleosis due to Epstein-Barr virus is a disease with good prognosis in children. The features of the disease may vary according to admission time, and this fact should be taken into consideration in the diagnosis.

Açıklama

Anahtar Kelimeler

Infectious Mononucleosis, Epstein-Barr Virus, Findings, Prognosis, Age, Admission Time, Children, Diagnosis, Cytomegalovirus, Ascites, Assay

Kaynak

Trakya Universitesi Tip Fakultesi Dergisi

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

25

Sayı

3

Künye