Prognostic Factors Affecting Survival in Small Cell Lung Cancer Patients

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dc.authoridÖZDEMİR, LEVENT/0000-0003-4578-9247;
dc.authorwosid, osman/HRD-6024-2023
dc.authorwosidÖZDEMİR, LEVENT/HJP-5498-2023
dc.authorwosid, Osman/AGR-7980-2022
dc.contributor.authorOzlen, Burcu
dc.contributor.authorHatipoglu, Osman Nuri
dc.contributor.authorOzdemir, Levent
dc.contributor.authorSut, Necdet
dc.contributor.authorAltiay, Gundeniz
dc.contributor.authorTabakoglu, Erhan
dc.date.accessioned2024-06-12T11:14:15Z
dc.date.available2024-06-12T11:14:15Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: Small cell lung cancer (SCLC) is an aggressive tumour with a poor clinical course, but responsive to both chemotherapy and radiotherapy. Some clinical and laboratory parameters can predict survival in SCLC. The aim of this study was to analyze the survival and identify the prognostic factors that influence survival in SCLC. Material andMethod: Forty six consecutive SCLC patients who were planned for chemotherapy, enrolled in this study prospectively. We recorded basic characteristic properties and factors affecting prognosis for each patient. We determined their survival time and survival curves were calculated by the method of Kaplan and Meier analysis. Results: Median survival time was 338 days (95% confidence interval: 243-432). Survival ratio for one month was 89%, for 6 months 62% and for one year 45%. Significiant parameters (p< 0.05) evaluated by univariate analysis followed by multivariate analysis. In multivariate analysis liver metastas (Relative Risk (RR): 4.99, 95% confidence interval: 1,21 -20,53), weight loss (RR: 11.3, 95% confidence interval 1,11-115,5) and low level of total protein after first chemotherapy (RR: 0.198, 95% confidence interval 0,06-0,63) were found as independent factors affecting survival. Conclusion: SCLC is a disease with high mortality. Prognostic factors that we found, can be supported by further investigations.en_US
dc.identifier.endpage12en_US
dc.identifier.issn2148-3620
dc.identifier.issn2148-5402
dc.identifier.issue1en_US
dc.identifier.startpage7en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23867
dc.identifier.volume11en_US
dc.identifier.wosWOS:000421849300002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofEurasian Journal Of Pulmonologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSmall Cell Lung Canceren_US
dc.subjectPrognostic Factorsen_US
dc.subjectKingdom Coordinating Committeeen_US
dc.subjectLaboratory Parametersen_US
dc.subjectPleural Effusionen_US
dc.subjectCarcinomaen_US
dc.subjectStageen_US
dc.subjectSubcommitteeen_US
dc.subjectMetastasesen_US
dc.subjectPredictorsen_US
dc.subjectTherapyen_US
dc.subjectDiseaseen_US
dc.titlePrognostic Factors Affecting Survival in Small Cell Lung Cancer Patientsen_US
dc.typeArticleen_US

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