The management of elevated intracranial pressure and sinus vein thrombosis associated with mastoiditis: the experience of eighteen patients

dc.authoridGurkas, Esra/0000-0003-3942-5105
dc.authoridBasaran Gundogdu, Elif/0000-0002-9140-4195
dc.authoridHavali, Cengiz/0000-0001-6275-0884
dc.authoridKARAL, YASEMIN/0000-0003-0096-6676
dc.authorwosidEkici, Arzu/AAK-7846-2020
dc.authorwosidGurkas, Esra/GRY-4538-2022
dc.authorwosidBasaran Gundogdu, Elif/KEE-5909-2024
dc.contributor.authorHavali, Cengiz
dc.contributor.authorInce, Hulya
dc.contributor.authorGundogdu, Elif Basaran
dc.contributor.authorGurkas, Esra
dc.contributor.authorKaral, Yasemin
dc.contributor.authorEkici, Arzu
dc.contributor.authorGundogdu, Ercan
dc.date.accessioned2024-06-12T10:56:04Z
dc.date.available2024-06-12T10:56:04Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose Cerebral sinus vein thrombosis (CSVT) associated with acute mastoiditis is a rare complication of acute otitis media. Elevated intracranial pressure (ICP) frequently occurs secondary to CSVT. The study aims to review the 5 years of experience of four medical centres to treat sigmoid sinus thrombosis and elevated intracranial pressure in children. Methods Patients with CSVT that developed secondary mastoiditis from 2016 through 2021 were evaluated in four centres from Turkey. Patients diagnosed with a preceding or synchronous mastoiditis and intracranial sinus thrombosis were included in the study. Magnetic resonance imaging (MRI), magnetic resonance venography (MRV), ICP measurements, ophthalmological examinations, thrombophilia studies and treatments for increased ICP have also been recorded. Results The study group comprises 18 children. Twelve patients were diagnosed with right-sided, six patients with left-sided sinus vein thrombosis. All of the patients had ipsilateral mastoiditis. The most common presenting symptoms were fever, ear pain, headache, visual disorders and vomiting. The most encountered neurologic findings were papilledema, strabismus and sixth cranial nerve palsy. ICP was over 20 cm H2O in eleven patients. Anticoagulant treatment, antibiotics, pressure-lowering lumbar puncture and lumboperitoneal shunt were among the treatment modalities. Conclusion Elevated ICP can damage the brain and optic nerve irreversibly, without treatment. For treating elevation of ICP associated with cerebral sinus thrombosis, pressure-lowering lumbar puncture (LP), acetazolamide therapy, optic nerve sheath fenestration (ONSF) and cerebrospinal fluid (CSF)-shunting procedures are suggested in case of deteriorated vision.en_US
dc.identifier.doi10.1007/s00381-021-05402-6
dc.identifier.endpage428en_US
dc.identifier.issn0256-7040
dc.identifier.issn1433-0350
dc.identifier.issue2en_US
dc.identifier.pmid34713346en_US
dc.identifier.scopus2-s2.0-85118201029en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage421en_US
dc.identifier.urihttps://doi.org/10.1007/s00381-021-05402-6
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19661
dc.identifier.volume38en_US
dc.identifier.wosWOS:000712209400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofChilds Nervous Systemen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCerebral Sinus Vein Thrombosisen_US
dc.subjectAcute Mastoiditisen_US
dc.subjectIntracranial Hypertensionen_US
dc.subjectLumboperitoneal Shuntingen_US
dc.subjectSinovenous Thrombosisen_US
dc.subjectOpening Pressureen_US
dc.subjectOtitis-Mediaen_US
dc.subjectChildrenen_US
dc.subjectComplicationsen_US
dc.subjectMulticenteren_US
dc.subjectUpdateen_US
dc.titleThe management of elevated intracranial pressure and sinus vein thrombosis associated with mastoiditis: the experience of eighteen patientsen_US
dc.typeArticleen_US

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