Frequency of gallstones after renal transplantation and factors that affect gallstone formation

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dc.authoridAltiparmak, Mehmet Riza/0000-0002-3579-1100
dc.authorwosidAltiparmak, Mehmet Riza/AAC-2508-2021
dc.contributor.authorCelik, Aykut Ferhat
dc.contributor.authorAltiparmak, Mehmet Riza
dc.contributor.authorPamuk, Guelsuem Emel
dc.contributor.authorPamuk, Oemer Nuri
dc.contributor.authorApaydin, Sueheyla
dc.date.accessioned2024-06-12T11:18:40Z
dc.date.available2024-06-12T11:18:40Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND: We investigated the frequency of gallstones (GSs) in our renal transplant recipients and evaluated the effects of various factors on GS formation. METHODS: One hundred and eight-two patients who had undergone renal transplantation at our center in the last 12 years were included in the study. Of these, 163 patients were followed up regularly, of whom 118 were using cyclosporine A (CsA). Abdominal ultrasonography of all patients was performed, and biochemical parameters were also determined. RESULTS: Median duration of patient follow-up was 36 months. GSs were diagnosed in 5 patients (3.1%). Mean age and follow-up duration of the CsA group were lower than those of the non-CsA group (p < 0.05 and p < 0.001, respectively). The frequency of GSs was 3.4% in the CsA group and 2.2% in the non-CsA group (p > 0.05). Median time to detect GS formation in the post-transplantation period was 85 months. The CsA group had a significantly shorter GS-free follow-up period than the non-CsA group (p = 0.008). According to Cox multivariate regression analysis, the only factor that affected GS formation in the post-transplantation period was the use of CsA. CONCLUSION: The use of CsA showed a trend toward increasing the risk of developing a GS sooner in the post-transplant period, particularly for young men.en_US
dc.identifier.doi10.1002/dat.20168
dc.identifier.endpage+en_US
dc.identifier.issn0090-2934
dc.identifier.issue10en_US
dc.identifier.scopus2-s2.0-54549112089en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage533en_US
dc.identifier.urihttps://doi.org/10.1002/dat.20168
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24911
dc.identifier.volume36en_US
dc.identifier.wosWOS:000250103500008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons Incen_US
dc.relation.ispartofDialysis & Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCyclosporine-Induced Cholestasisen_US
dc.subjectRecipientsen_US
dc.subjectCholelithiasisen_US
dc.subjectTherapyen_US
dc.subjectCholecystectomyen_US
dc.subjectLipoproteinsen_US
dc.subjectManagementen_US
dc.subjectSecretionen_US
dc.titleFrequency of gallstones after renal transplantation and factors that affect gallstone formationen_US
dc.typeArticleen_US

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