Continuous venovenous hemodialysis may be effective in digoxin removal in digoxin toxicity: A case report

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dc.authoridkurultak, ilhan/0000-0001-5607-1375
dc.authoridGokalp, Cenk/0000-0003-3909-7973
dc.authoridAygun, Gokhan/0000-0001-6915-9843
dc.authorwosidGokalp, Cenk/AGW-1853-2022
dc.authorwosidkurultak, ilhan/V-1616-2019
dc.contributor.authorGokalp, Cenk
dc.contributor.authorDogan, Aysun Fatma
dc.contributor.authorAygun, Guray
dc.contributor.authorKurultak, Ilhan
dc.contributor.authorUstundag, Sedat
dc.date.accessioned2024-06-12T10:50:33Z
dc.date.available2024-06-12T10:50:33Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractDigoxin is a cardiac glycoside that is used for the treatment of heart failure and atrial fibrillation. Besides its careful close follow-up, toxicity affects nearly 1% of congestive heart failure patients. Cessation of the drug, appropriate electrolyte and rhythm control and digoxin-Fab antibody are the mainstay for toxicity treatment in these patients. As known, hemodialysis and peritoneal dialysis are not effective by the means of digoxin removal. We present a 66-year-old patient who admitted to hospital with digoxin toxicity and severe acute kidney injury. The patient was treated with continuous venovenous hemodialysis because of her hypervolemia, hyperkalemia, cardiac instability, and the thought of probable decrease in digoxin levels concerning the continuous nature of solute clearance. Without the treatment using digoxin-specific Fab antibodies, the patient's digoxin level was decreased successfully with continuous venovenous hemodialysis. In conclusion, continuous venovenous hemodialysis may be a treatment option in digoxin toxicity especially those who suffer from severe renal dysfunction and cannot access digoxin antidote.en_US
dc.identifier.doi10.1111/hdi.12867
dc.identifier.endpageE60en_US
dc.identifier.issn1492-7535
dc.identifier.issn1542-4758
dc.identifier.issue4en_US
dc.identifier.pmid32770621en_US
dc.identifier.scopus2-s2.0-85089083072en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpageE58en_US
dc.identifier.urihttps://doi.org/10.1111/hdi.12867
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18048
dc.identifier.volume24en_US
dc.identifier.wosWOS:000556569400001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofHemodialysis Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectContinuous Venovenous Hemodialysisen_US
dc.subjectDigoxin Toxicityen_US
dc.subjectHeart Failureen_US
dc.subjectClinical Pharmacokineticsen_US
dc.subjectIntoxicationen_US
dc.subjectPatienten_US
dc.titleContinuous venovenous hemodialysis may be effective in digoxin removal in digoxin toxicity: A case reporten_US
dc.typeArticleen_US

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