Francisella tularensis and Tularemia in Turkey

Basit Öğe Kaydı
dc.authoridGurcan, Saban/0000-0002-5052-481X
dc.authorwosidGurcan, Saban/D-2754-2017
dc.contributor.authorGurcan, Saban
dc.date.accessioned2024-06-12T11:16:44Z
dc.date.available2024-06-12T11:16:44Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractFrancisella tularensis is a small gram-negative aerobic bacillus which was named after Edward Francis and the location (Tulare County, California) where the organism was discovered. F.tularensis includes three subspecies known as tularensis (type A biovar), holarctica (type B biovar) and mediasiatica. Tularemia (rabbit fever) is a rare and primarily rural disease which may be transmitted by ingestion, inhalation, or by direct skin contact with rabbits, other rodents and by blood-sucking arthropods. Infection occurs in different forms, such as typhoidal, pneumonic, oculoglandular, oropharyngeal, ulceroglandular, and glandular. The incubation period is about 3-5 days, but may vary between 1 to 21 days, and symptoms vary based on the mode of infection. Infections by F.tularensis subsp. tularensis are generally presented as ulceroglandular form and cause more severe diseases leading 5-60% mortality in untreated patients. F.tularensis subsp. holarctica which is a less virulent organism, mainly cause oropharyngeal form of infection especially in Europe countries as well as in Turkey. Since F.tularensis is extremely virulent organism and is difficult to culture on standard media, laboratory diagnosis is mainly based on the serological assays such as microagglutination or ELISA tests. Streptomycin or gentamycin (for 10-14 days) are the first choise antibiotics for the treatment. Tularemia becomes a reemerging zoonosis in Turkey. The first published tularemia epidemic in Turkey had been reported in 1936 from Thrace region (Luleburgaz town), and the second was in 1945 again in the same location. In recent years, tularemia outbreaks were reported from various regions of Turkey. The reliable data were obtained after 2005 because of the inclusion of this infection into Group C of notification system of communicable diseases by Turkish Ministry of Health. A total of 431 confirmed cases were reported from various provinces according to data of the year 2005. In this review, general characteristics of F.tularensis and its infections have been discussed emphasizing the data related with tularemia in Turkey.en_US
dc.identifier.endpage636en_US
dc.identifier.issn0374-9096
dc.identifier.issue4en_US
dc.identifier.pmid18173084en_US
dc.identifier.scopus2-s2.0-45849096738en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage621en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24427
dc.identifier.volume41en_US
dc.identifier.wosWOS:000251478700018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherAnkara Microbiology Socen_US
dc.relation.ispartofMikrobiyoloji Bultenien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTularemiaen_US
dc.subjectFrancisella Tularensisen_US
dc.subjectTurkeyen_US
dc.subjectLinked-Immunosorbent-Assayen_US
dc.subjectDiagnosisen_US
dc.subjectOutbreaken_US
dc.subjectSeroprevalenceen_US
dc.subjectAntibodiesen_US
dc.subjectAntigensen_US
dc.subjectDiseaseen_US
dc.subjectRegionen_US
dc.subjectPcren_US
dc.titleFrancisella tularensis and Tularemia in Turkeyen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu