Semi-quantitative investigation of primary tumor and bone metastasis in lung cancer patients using the PET-CT approach

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dc.contributor.authorKandemir, Ozan
dc.contributor.authorKarakus, Kayhan
dc.contributor.authorKatrancioglu, Ozgur
dc.contributor.authorSarikaya, Ali
dc.date.accessioned2024-06-12T10:54:56Z
dc.date.available2024-06-12T10:54:56Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Although advanced diagnostic and therapeutic development are achieved, lung cancer is the most leading cause of death. The stage of tumor is still the most important factor in determining the prognosis of cancer. Purpose: The overarching goal of this study is to understand the relationship between the maximum standard uptake value (SUVmax) and bone metastasis using the PET-CT approach in lung cancer prognosis and survival research. Materials and methods: The PET-CT analyses of previously diagnosed totally 86 lung cancer patients were retrospectively studied. Primer tumor standard uptake values for each patient were meticulously calculated and correlated with bone metastasis. Results: The demographics of the 86 patients is as follows; 79 man, 7 women with an age average of 59.44 +/- 5.99, youngest being 46 and oldest 72. The number of small cell (SCC) and non-small cell lung cancer (NSCLC) patients were 10 (11.6%) and 76 (88.4%), respectively. Additionally, bone metastasis was detected in 35 (40.7%) patients. The patients were divided in 4 categories based on the observed primer tumor sizes of 0-3 cm (23.3%), 3-5 cm (27.9%), 5-7 cm (32.6%), and larger than 7 cm (16.3%). Patients with bone metastasis (35 in total) were divided in 2 categories based on the number of metastasis of being less than 3 (45.7%) and more than 3 (54.5%). We also used SUVmax values to clarify the study. 31.4% of the total patients had the SUVmax value lower than 10 and 68.6% of them had higher. 68.6% of the bone metastasis patients had SUV values lower than 8 and 31.4% of them had higher than 8. Conclusion: The present study suggests a 27.2% positive relationship in primary tumor SUVmax value and tumor size. Although the average bone metastasis SUV with primary tumor SUV values higher than 10 is higher than the ones lower than 10, this difference did not generate a statistically significant data for cancer patients.en_US
dc.identifier.endpage2631en_US
dc.identifier.issn1940-5901
dc.identifier.issue9en_US
dc.identifier.pmid25356118en_US
dc.identifier.startpage2624en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19232
dc.identifier.volume7en_US
dc.identifier.wosWOS:000345121000027en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal Of Clinical And Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Metastasisen_US
dc.subjectFluoro-2-Deoxy-D-Glucose Positron Emission Tomographyen_US
dc.subjectLung Canceren_US
dc.subjectStandard Uptake Valueen_US
dc.subjectPositron-Emission-Tomographyen_US
dc.subjectDistant Metastasesen_US
dc.subjectPrognostic Valueen_US
dc.subjectSolitaryen_US
dc.titleSemi-quantitative investigation of primary tumor and bone metastasis in lung cancer patients using the PET-CT approachen_US
dc.typeArticleen_US

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