Uveitis-related Factors in Patients With Spondyloarthritis: TReasure Real-Life Results

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dc.authoridGonullu, Emel/0000-0002-6990-4206
dc.authoridCoşkun, Belkıs Nihan/0000-0003-0298-4157
dc.authoridKanıtez, Nilüfer Alpay/0000-0003-1185-5816
dc.authoridkucuksahin, orhan/0000-0003-4530-2304
dc.authoridATAGUNDUZ, PAMIR/0000-0002-6393-7461
dc.authoridErden, Abdulsamet/0000-0002-8084-2018
dc.authoridKaradag, Omer/0000-0002-3443-3117
dc.authorwosidGonullu, Emel/AAK-7851-2021
dc.authorwosidCoşkun, Belkıs Nihan/AAG-7155-2021
dc.authorwosidKanıtez, Nilüfer Alpay/W-7332-2019
dc.authorwosidKOCA, SULEYMAN SERDAR/HJY-2666-2023
dc.authorwosidpehlivan, yavuz/AAG-8227-2021
dc.authorwosidkucuksahin, orhan/GZA-3287-2022
dc.authorwosidYağız, Burcu/JQW-5031-2023
dc.contributor.authorBilge, Nazife Sule Yasar
dc.contributor.authorKalyoncu, Umut
dc.contributor.authorAtagunduz, Pamir
dc.contributor.authorDalkilic, Ediz
dc.contributor.authorPehlivan, Yavuz
dc.contributor.authorKucuksahin, Orhan
dc.contributor.authorBes, Cemal
dc.date.accessioned2024-06-12T11:17:34Z
dc.date.available2024-06-12T11:17:34Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPURPOSE: Spondyloarthritis (SpA) is a group of diseases with overlapping skeletal and extra-articular features. Acute anterior uveitis (AAU) is the most common extra-articular manifestation of SpA. The relation between AAU and SpA is well defined in the current literature. Our study aims to analyze the frequency and factors associated with AAU in different forms of SpA in a large nationwide cohort of Turkish SpA patients. DESIGN: Retrospective cohort study. METHODS: The data were obtained from the TReasure database, which compiles data from records of the web-based Rheumatoid Arthritis (RA) and SpA patients treated with biological disease-modifying anti-rheumatismal drugs from different regions of Turkey. The clinical characteristics of SpA and uveitis are recorded. RESULTS: Data of the 4,297 SpA patients were included in the study. Overall, 475 of 4,297 patients (11.0%) had experienced 1 or more episodes of uveitis. SpA patients with older age (P<.001), a smoking history (P=.004), delayed diagnosis (P=.001), longer disease duration (P<.001), arthritis (P<.001), positive HLA-B27 (P<.001), a family history of SpA (P<.001), and radiographic damage (presence of sacroiliitis, syndesmophytes, bamboo spine, hip involvement) (P<.001 for all) more commonly had uveitis. On the other hand, uveitis was less prevalent in patients with psoriasis and psoriatic arthritis (P<.001 for both). CONCLUSION: Uveitis may be the key feature leading to SpA diagnosis. Patients with radiographic damage and long disease duration have an increased risk for uveitis in both male and female SpA patients. Patients with uveitis should be referred to a rheumatologist for a thorough evaluation of SpA. ((C) 2021 Elsevier Inc. All rights reserved.)en_US
dc.identifier.doi10.1016/j.ajo.2021.03.026
dc.identifier.endpage64en_US
dc.identifier.issn0002-9394
dc.identifier.issn1879-1891
dc.identifier.pmid33826929en_US
dc.identifier.scopus2-s2.0-85106321610en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage58en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajo.2021.03.026
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24764
dc.identifier.volume228en_US
dc.identifier.wosWOS:000707001200008en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAmerican Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing-Spondylitisen_US
dc.subjectAnterior Uveitisen_US
dc.titleUveitis-related Factors in Patients With Spondyloarthritis: TReasure Real-Life Resultsen_US
dc.typeArticleen_US

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