Breast Cancer Radiotherapy-induced Cardiotoxicity

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dc.authoridCosar, Rusen/0000-0002-7953-8887
dc.authorwosidCosar, Rusen/GQP-7875-2022
dc.contributor.authorNurlu, Dilek
dc.contributor.authorCosar, Rusen
dc.contributor.authorParlar, Sule
dc.contributor.authorUzal, Cem
dc.date.accessioned2024-06-12T10:55:11Z
dc.date.available2024-06-12T10:55:11Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn the multimodality treatment of breast cancer, adjuvant radiotherapy (RT) has an important role in achieving local control and increasing survival. Cardiac toxicity due to breast RT, especially left-sided breast RT, is rare but clearly recognizable. As overall survival rates are steadily increasing, long-term toxicities also become increasingly important in terms of late cardiac events, possibly caused by RT. Even small doses for the heart are thought to increase the risk of cardiac toxicity. Advanced radiation techniques such as intensity-modulated radiation therapy, volumetric-modulated arc RT, deep inspiration breath-hold techniques, and prone positioning for pendular breast can eliminate the heart from the primary beams. In addition to mean heart dose, breast cancer RT planning should also include constraints for cardiac subvolumes. Especially for patients who have pre-existing such as cardiovascular disease, diabetes mellitus, dyslipidemia, arterial hypertension, lifestyle factor (tobacco smoking, alcohol, physical inactivity, and poor nutrition), and physicians have to be careful about cardiotoxicity. Radiation oncologists and cardiology specialists should provide closely cooperating regular and long-term followup. This will provide the improvement of patient outcomes.en_US
dc.identifier.doi10.5505/tjo.2022.S1006
dc.identifier.endpage43en_US
dc.identifier.issn1300-7467
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85127643080en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage35en_US
dc.identifier.urihttps://doi.org/10.5505/tjo.2022.S1006
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19327
dc.identifier.volume37en_US
dc.identifier.wosWOS:001132582400006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofTurk Onkoloji Dergisi-Turkish Journal Of Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast Canceren_US
dc.subjectCardiotoxicityen_US
dc.subjectRadiotherapyen_US
dc.subjectRadical-Mastectomyen_US
dc.subjectUk Standardizationen_US
dc.subjectRadiation-Therapyen_US
dc.subjectHeart-Diseaseen_US
dc.subjectFollow-Upen_US
dc.subjectIrradiationen_US
dc.subjectHypofractionationen_US
dc.subjectChemotherapyen_US
dc.subjectHolden_US
dc.subjectReduceen_US
dc.titleBreast Cancer Radiotherapy-induced Cardiotoxicityen_US
dc.typeReview Articleen_US

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