Thrombosis in systemic lupus erythematosus
Küçük Resim Yok
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer-Verlag
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Thrombosis in the venous or arterial system is quite common in systemic lupus erythematosus (SLE). We describe a young female patient whose first presentation was in the form of deep venous thrombosis of the right lower extremity. Her family history for thrombosis was positive and further studies revealed her to have SLE. Genetic studies showed that she had thrombophilic mutations of factor V, prothrombin and methylene tetrahydrofolate reductase genes. Her therapeutic response to anticoagulant therapy was satisfactory. The presence of inherited thrombophilic mutations must be searched for in SLE patients with thrombosis, especially in cases with a positive family history.
Açıklama
Anahtar Kelimeler
Systemic Lupus Erythematosus (SLE), Deep Venous Thrombosis (DVT), Thrombophilia, Factor V Leiden, Prothrombin (G20210A) Mutation, Activated Protein-C, G-A Mutation, Venous Thrombosis, Prothrombin Gene, Antiphospholipid Antibodies, Resistance, Population, Disease, Risk
Kaynak
Clinical Rheumatology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
22
Sayı
4-5
