Seroprevalance of Bordetella pertussis antibodies among healthy adolescent girls in Edirne
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
E M H Swiss Medical Publishers Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Immune response against pertussis can be induced by infection and/or vaccination and vaccine induced immunity is known to wane within the decade following vaccination. Our aim was to assess the pertussis immune response among adolescent girls in the province of Edirne in Turkey. In addition we determined the relationship between the immune response and age, residence, and vaccination status. Material and methods: Serum samples were collected from 3 59 adolescent girls, 12 to 17 years old. The subjects were selected by systematic randomisation from school rosters and sampled by age and urban-rural residence strata proportional to the corresponding distributions in the Edirne population. Pertussis immunity was determined by an in-house quantitative ELISA method for anti-PT and anti-FHA antibodies. Results: Protective levels of antibody (>10 EU/ml) for anti-pertussis toxin and anti-filamentons heamagglutinin were found in 95.3% and 97.2% of the overall study group respectively. In 12- to 14-year-olds protective levels were shown in 94.1% and 97.0%, in 15- to 17-year-olds in 97.5% and 97.5%, In rural areas in 96.7% and 97.5%, and in urban areas in 94.5% and 97.5%, respectively (p >0.05). Conclusion: The high percentages of protective levels of antibodies in our study population might be an indicator of previous infections, which are a threat to infants who have not completed primary immunisation. In this respect, adult immunisation should be considered.
Açıklama
Anahtar Kelimeler
Immunity, Adolescent Girls, Pertussis, Turkey, Seroepidemiology, Vaccination
Kaynak
Swiss Medical Weekly
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
135
Sayı
35-36
