Long-term survival in a patient with brain metastases preceding the diagnosis of endometrial cancer -: Report of two cases and review of the literature
Küçük Resim Yok
Tarih
2001
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Amer Assoc Neurological Surgeons
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Only five patients found to have brain metastasis preceding the diagnosis of endometrial cancer have been reported in the literature, and none of these survived beyond 38 months. The authors report on two patients with primary endometrial cancer who initially presented with cerebral metastasis. One of these patients died of disease 15 months after diagnosis. The other patient is still alive, with no evidence of disease, 171 months after she underwent radiosurgery for a solitary brain metastasis, aggressive cytoreductive abdominal and pelvic surgery, and doxorubicin-based chemotherapy. To the best of their knowledge, the authors believe that no similar observation has been made for any primary gynecological neoplasm, including endometrial, ovarian, or cervical cancer. This is the first report documenting that survival beyond one decade may be achieved after intensive multimodal therapy in selected patients in whom a solitary brain metastasis has been found before diagnosis of endometrial cancer. Aggressive therapy appears to be warranted in these patients.
Açıklama
Anahtar Kelimeler
Endometrial Cancer, Brain Metastasis, Central Nervous System Metastasis, Long-Term Survival, Carcinoma
Kaynak
Journal Of Neurosurgery
WoS Q Değeri
Q1
Scopus Q Değeri
Cilt
94
Sayı
5
