Superparamagnetic Iron Oxide Enhanced Magnetic Resonance Imaging in the Detection of Malignant Liver Lesions

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dc.authorwosidUmit, Hasan/T-6236-2019
dc.authorwosidTosun, Alptekin/AAA-1350-2021
dc.contributor.authorCagli, Bekir
dc.contributor.authorTemizoz, Osman
dc.contributor.authorGenchellac, Hakan
dc.contributor.authorUmit, Hasan
dc.contributor.authorTosun, Alptekin
dc.contributor.authorCakir, Bilge
dc.date.accessioned2024-06-12T11:15:49Z
dc.date.available2024-06-12T11:15:49Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To determine the value of superparamagnetic iron oxide (SPIO)-enhanced MR imaging in malignant liver lesions. Materials and Methods: Twenty patients with various hepatic masses or metastases were investigated with 1 tesla MR. T1-weighted FLASH and double- echo TSE T2-weighted sequences were applied before and after contrast injection. Defining statistics were prepared according to pre and postcontrast signal intensity measurements. Results: In this study there were 11 patients with metastases, 4 patients with hemangioma, 4 patients with HCC and one patient with a hemangioma and a metastasis at the same time. In cases wheret we found only hemangiomas, in all sequences, S/N ratios (p=0.043) and T2-weighted double-echo TSE with long TE SI change (p=0.043) were significant. While in the hemangiomas in T2-weighted double-echo TSE with long TE there is an decrease in the C/N ratios; in cases with metastasis and HCC, compared to other sequences significant increase in C/N ratio in T2-weighted double-echo TSE with short TE sequences was detected. Conclusion: SPIO-enhanced MR imaging can be used as a non-invasive radiologic technique for the detection focal liver lesions, to determine the number of lesions and also has a value in differentiating the benign lesions (especially hemangiomas) from primary tumors or metastatic malignant lesions.en_US
dc.identifier.endpage292en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue3en_US
dc.identifier.startpage286en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24087
dc.identifier.volume28en_US
dc.identifier.wosWOS:000295492900012en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSuperparamagnetic Iron Oxide (SPIO)en_US
dc.subjectContrast-Noise Ratioen_US
dc.subjectMR Imagingen_US
dc.subjectT1-Weighted FLASH And T2-Weighted Double-Echo TSE Sequencesen_US
dc.subjectFocal Hepatic-Lesionsen_US
dc.subjectContrast Agentsen_US
dc.subjectSpiral Cten_US
dc.subjectMren_US
dc.subjectFerumoxidesen_US
dc.subjectMetastasesen_US
dc.subjectSafetyen_US
dc.titleSuperparamagnetic Iron Oxide Enhanced Magnetic Resonance Imaging in the Detection of Malignant Liver Lesionsen_US
dc.typeArticleen_US

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