Relationship between second-trimester amniotic fluid levels of Prokineticin-1 and Matrix Metalloproteinase-2 with adverse pregnancy outcome

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dc.authorwosidSAYIN, N. CENK/A-5801-2018
dc.contributor.authorErzincan, Selen G.
dc.contributor.authorVarol, Fusun G.
dc.contributor.authorInan, Cihan
dc.contributor.authorSayin, N. Cenk
dc.date.accessioned2024-06-12T11:12:56Z
dc.date.available2024-06-12T11:12:56Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractTo investigate the levels of Prokineticin-1 (PROK1) and matrix metalloproteinase-2 (MMP-2) in second-trimester amniotic fluid (AF). AF samples were investigated in 81 patients. AF-PROK1 and AF-MMP-2 were not significantly associated with adverse pregnancy outcomes (preeclampsia, intrauterine growth retardation, spontaneous preterm birth, gestational diabetes, gestational hypertension). AF-PROK1 levels in patients with abnormal first-trimester screening were significantly higher than those who underwent amniocentesis due to abnormal second-trimester screening tests (p = .04). AF-PROK1 or AF-MMP-2 do not have a role in the prediction of adverse pregnancy outcomes. (c) 2017 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipTrakya University [2015/123]en_US
dc.description.sponsorshipThis study was supported by Research Fund of the Trakya University (Project number: 2015/123).en_US
dc.identifier.doi10.1016/j.placenta.2017.12.015
dc.identifier.endpage27en_US
dc.identifier.issn0143-4004
dc.identifier.issn1532-3102
dc.identifier.pmid29405963en_US
dc.identifier.scopus2-s2.0-85038824087en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage25en_US
dc.identifier.urihttps://doi.org/10.1016/j.placenta.2017.12.015
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23368
dc.identifier.volume62en_US
dc.identifier.wosWOS:000424371800004en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co Ltden_US
dc.relation.ispartofPlacentaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectProkineticin 1en_US
dc.subjectMetalloproteinase (MMP)-2en_US
dc.subjectAmniotic Fluiden_US
dc.subjectPlacentaen_US
dc.subjectAdverse Pregnancy Outcomesen_US
dc.subjectEndothelial Growth-Factoren_US
dc.subjectEg-Vegfen_US
dc.titleRelationship between second-trimester amniotic fluid levels of Prokineticin-1 and Matrix Metalloproteinase-2 with adverse pregnancy outcomeen_US
dc.typeArticleen_US

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