Ultrasonographically detected hepatosteatosis independently predicts the presence and severity of coronary artery disease
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Makerere Univ, Coll Health Sciences,Sch Med
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Nonalcoholic fatty liver disease (NAFLD) has shown to be associated with coronary artery disease (CAD) Objectives: The aim of our study was to evaluate the association between the presence and severity of CAD and NAFLD. Methods: The study group consisted of 153 patients who underwent coronary angiographies. Patients were categorized into CAD and non-CAD groups. CAD severity was determined by the number of CAD-involved arteries and the vessel score multiplied by Gensini score, the latter judging CAD severity. Fatty liver was diagnosed by abdominal ultrasonography (USG), with the patients being categorized by the degree of hepatosteatosis, as Grade 0, Grade 1, and Grade 2-3. Results: Among the whole study population, 47.1% of patients (n=72) were female and 52.9% of patients (n=81) were male. Forty-three patients had normal coronary arteries; 27 patients had non-critical CAD and side branch disease; and 83 patients had clinically significant CAD (stenosis>50%). The rate of CAD and Gensini score were significantly different between Grade 0, 1 and 2-3 hepatosteatosis groups (p<0.05). Patients with CAD had a significantly higher AST level than those without (p<0.05). Conclusions: Ultrasonographically detected hepatosteatosis independently predicts the presence and severity of CAD.
Açıklama
Anahtar Kelimeler
Nonalcoholic Fatty Liver Disease, Gensini Score, Obesity, Nonalcoholic Fatty Liver, Gamma-Glutamyl-Transferase, Carotid Atherosclerosis, Association, Nafld, Risk, Steatohepatitis, Diagnosis
Kaynak
African Health Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
22
Sayı
2
